Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48070 | 0.87 | SIGMAR1 (0.64) | SIGMAR1CYP2A6TPSAB1PDE3BPDE3A | |
| SCHEMBL3812143 | 0.85 | SIGMAR1 (0.50) | SIGMAR1CYP2A6TPSAB1KDM4ERAD52 | |
| SCHEMBL3813009 | 0.84 | SIGMAR1 (0.60) | SIGMAR1CYP2A6PDE10APTPRCPTPN6 | |
| SCHEMBL3817648 | 0.81 | SIGMAR1 (0.49) | SIGMAR1CYP2A6TPSAB1KDM4ERAD52 | |
| SCHEMBL3816651 | 0.80 | SIGMAR1 (0.53) | SIGMAR1CYP2A6TPSAB1KDM4EPOLB | |
| SCHEMBL16331135 | 0.80 | SIGMAR1 (0.52) | SIGMAR1CYP2A6TPSAB1KDM4ETSHR | |
| SCHEMBL3812339 | 0.80 | SIGMAR1 (0.48) | SIGMAR1CYP2A6TPSAB1RAD52PAX8 | |
| SCHEMBL13873189 | 0.80 | SIGMAR1 (0.57) | SIGMAR1CYP2A6PDE10APTPRCPTPN6 | |
| SCHEMBL3815301 | 0.78 | SIGMAR1 (0.49) | SIGMAR1CYP2A6TPSAB1KDM4EPDE10A | |
| SCHEMBL3810177 | 0.78 | SIGMAR1 (0.52) | SIGMAR1CYP2A6KDM4EPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186594-B1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6797726-B1 | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1186594-A1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |