Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 3/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382428 | 0.83 | ACP3 (0.43) | CNR2ACP3POLQCYP3A4ALDH1A1 | |
| SCHEMBL382108 | 0.82 | ALDH1A1 (0.41) | CNR1CPA1CYP3A4ALDH1A1 | |
| SCHEMBL167206 | 0.82 | CNR2 (0.42) | CNR2ACP3POLQCYP3A4ALDH1A1 | |
| SCHEMBL380984 | 0.81 | CNR2 (0.41) | CNR2ACP3POLQCYP3A4ALDH1A1 | |
| SCHEMBL19244866 | 0.81 | CNR2 (0.41) | CNR2ACP3POLQCYP3A4ALDH1A1 | |
| SCHEMBL19244827 | 0.81 | CNR2 (0.39) | CNR2ACP3POLQCYP3A4ALDH1A1 | |
| SCHEMBL19244870 | 0.79 | CNR2 (0.40) | CNR2ACP3POLQCYP3A4ALDH1A1 | |
| SCHEMBL16674049 | 0.78 | MEN1 (0.37) | CNR1CPA1CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL382042 | 0.76 | CNR2 (0.40) | CNR2ACP3CYP3A4ALDH1A1POLB | |
| SCHEMBL381588 | 0.76 | CNR1 (0.45) | CNR1ACP3CYP3A4ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408751-B1 | Substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof | BAYER IP GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |
| EP-2408751-A1 | Substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof | Bayer Pharma Aktiengesellschaft (DE) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010105770-A1 | SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-23 | — | — | WO | disclosed |