Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 4/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14677795 | 0.87 | — | — | |
| SCHEMBL3831959 | 0.79 | — | — | |
| SCHEMBL27577577 | 0.79 | PIM1 (0.38) | PIM1PIM2KCNH2 | |
| SCHEMBL1771284 | 0.71 | CYP3A4 (0.32) | — | |
| SCHEMBL4515374 | 0.69 | CA1 (0.38) | — | |
| SCHEMBL13713182 | 0.68 | CA1 (0.34) | — | |
| SCHEMBL4749383 | 0.68 | OPRM1 (0.44) | — | |
| SCHEMBL7621116 | 0.67 | CHRM5 (0.42) | — | |
| SCHEMBL1964997 | 0.67 | MME (0.33) | — | |
| SCHEMBL6602948 | 0.66 | CHRM5 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796466-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2009-09-02 | — | — | EP | disclosed |
| EP-1796466-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006002047-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2006-01-05 | — | — | WO | disclosed |