Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.42 |
| ▸ | ITGAV | P06756 | 3/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | MTTP | P55157 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383239 | 0.85 | ITGB3 (0.55) | ITGB3ITGAVITGA2BFFAR4NPY2R | |
| SCHEMBL6798772 | 0.85 | ITGB3 (0.44) | ITGB3ITGAVITGA2BFFAR4NPY2R | |
| SCHEMBL382678 | 0.84 | ITGB3 (0.44) | ITGB3ITGAVITGA2BFFAR4NPY2R | |
| SCHEMBL384053 | 0.83 | ITGB3 (0.41) | ITGB3ITGAVITGA2BFFAR4MAPT | |
| SCHEMBL382037 | 0.82 | ITGB3 (0.55) | ITGB3ITGAVITGA2BFFAR4NPY2R | |
| SCHEMBL382777 | 0.81 | ITGB3 (0.55) | ITGB3ITGAVITGA2BFFAR4NPY2R | |
| SCHEMBL7544338 | 0.80 | ITGB3 (0.41) | ITGB3ITGAVITGA2BFFAR4NPY2R | |
| SCHEMBL382307 | 0.79 | ITGB3 (0.47) | ITGB3ITGAVITGA2BKMT2ALMNA | |
| SCHEMBL6505536 | 0.78 | ITGB3 (0.48) | ITGB3ITGAVITGA2BKMT2AHDAC8 | |
| SCHEMBL6796296 | 0.78 | ITGB3 (0.41) | ITGB3ITGAVITGA2BFFAR4NPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |