Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 2/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HRH2 | P25021 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3824679 | 0.96 | HRH3 (0.57) | HTR1ADRD2HTR2APLK1HRH3 | |
| SCHEMBL1979469 | 0.93 | HRH3 (0.59) | HTR1ADRD2HTR2APLK1HRH3 | |
| SCHEMBL2025211 | 0.89 | HRH3 (0.64) | HTR1ADRD2HTR2APLK1HRH3 | |
| Hydrochloric Acid SCHEMBL1977487 | 0.88 | HRH3 (0.62) | HTR1ADRD2HTR2APLK1HRH3 | |
| SCHEMBL4495175 | 0.86 | HRH3 (0.68) | HTR1ADRD2HTR2APLK1HRH3 | |
| SCHEMBL14241012 | 0.86 | HRH3 (0.72) | HTR1ADRD2HTR2APLK1HRH3 | |
| SCHEMBL4486197 | 0.86 | HRH3 (0.72) | HTR1ADRD2HTR2APLK1HRH3 | |
| SCHEMBL3828820 | 0.83 | HRH3 (0.74) | HRH3KDM4EKMT2AHTTALDH1A1 | |
| SCHEMBL4465038 | 0.82 | HRH3 (0.53) | HRH3KDM4EKMT2AHTTALDH1A1 | |
| SCHEMBL3824026 | 0.82 | KDM4E (0.64) | DRD2HRH3KDM4EKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906547-B2 | Azabicylic compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2011-03-15 | — | — | US | disclosed |
| US-20090312389-A1 | Azabicylic compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2009-12-17 | — | — | US | disclosed |
| EP-2133333-A1 | New azabicyclic derivatives, method of preparing same and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2009-12-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312389-A1 | Azabicylic compounds, a process for their preparation and pharmaceutical compositions containing them | CHAT, MAOB, ALKBH2 | HTR1A 34/4885DRD2 167/4885HTR2A 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.