Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | F12 | P00748 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11323612 | 1.00 | KMT2A (0.65) | KMT2AMEN1POLBGRIN2BGRIN1 | |
| SCHEMBL14125504 | 1.00 | KMT2A (0.65) | KMT2AMEN1POLBGRIN2BGRIN1 | |
| SCHEMBL19791239 | 0.80 | PRSS1 (0.60) | KMT2AMEN1GRIN2BPLAUPRSS1 | |
| SCHEMBL18938347 | 0.80 | KMT2A (0.61) | KMT2AMEN1POLBGRIN2BGRIN1 | |
| SCHEMBL24136574 | 0.79 | KMT2A (1.00) | KMT2AMEN1POLBGRIN2BGRIN1 | |
| SCHEMBL139363 | 0.79 | KMT2A (1.00) | KMT2AMEN1POLBGRIN2BGRIN1 | |
| SCHEMBL24662980 | 0.79 | KMT2A (1.00) | KMT2AMEN1POLBGRIN2BGRIN1 | |
| Benzamidoxime SCHEMBL102483 | 0.78 | KMT2A (0.58) | KMT2AMEN1POLBGRIN2BGRIN1 | |
| Benzamidoxime SCHEMBL872652 | 0.78 | KMT2A (0.58) | KMT2AMEN1POLBGRIN2BGRIN1 | |
| SCHEMBL22872296 | 0.78 | KMT2A (0.58) | KMT2AMEN1POLBGRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3366311-B1 | HYDRAZINO-1H-IMIDAZOQUINOLIN-4-AMINES AND CONJUGATES MADE THEREFROM | 3M INNOVATIVE PROPERTIES CO (US) | 2020-02-26 | — | — | EP | disclosed |
| US-10406142-B2 | Hydrazino 1H-imidazoquinolin-4-amines and conjugates made therefrom | 3M LNNOVATIVE PROPERTIES COMPANY (US) | 2019-09-10 | — | — | US | disclosed |
| EP-3366311-A1 | HYDRAZINO 1H-IMIDAZOQUINOLIN-4-AMINES AND CONJUGATES MADE THEREFROM | 3M Innovative Properties Co. (US) | 2018-08-29 | — | — | EP | disclosed |
| EP-2718292-B1 | HYDRAZINO 1H-IMIDAZOQUINOLIN-4-AMINES AND CONJUGATES MADE THEREFROM | 3M INNOVATIVE PROPERTIES CO (US) | 2018-03-14 | — | — | EP | disclosed |
| US-20170173164-A1 | HYDRAZINO 1H-IMIDAZOQUINOLIN-4-AMINES AND CONJUGATES MADE THEREFROM | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2017-06-22 | — | — | US | disclosed |
| US-9585968-B2 | Hydrazino 1H-imidazoquinolin-4-amines and conjugates made therefrom | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-03-07 | — | — | US | disclosed |
| CN-104487433-B | Triazolone compounds as mPGES-1 inhibitors | 格兰马克药品股份有限公司 | 2016-12-07 | — | — | CN | disclosed |
| US-20150352218-A1 | HYDRAZINO 1H-IMIDAZOQUINOLIN-4-AMINES AND CONJUGATES MADE THEREFROM | 3M INNOVATIVE PROPERTIES COMPANY | 2015-12-10 | — | — | US | disclosed |
| US-9107958-B2 | Hydrazino 1H-imidazoquinolin-4-amines and conjugates made therefrom | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-18 | — | — | US | disclosed |
| CN-104487433-A | Triazolone compounds as mpges-1 inhibitors | GLENMARK PHARMACEUTICALS SA | 2015-04-01 | — | — | CN | disclosed |
| US-20140286988-A1 | HYDRAZINO 1H-IMIDAZOQUINOLIN-4-AMINES AND CONJUGATES MADE THEREFROM | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-09-25 | — | — | US | disclosed |
| EP-2718292-A1 | HYDRAZINO 1H-IMIDAZOQUINOLIN-4-AMINES AND CONJUGATES MADE THEREFROM | 3M Innovative Properties Company (US) | 2014-04-16 | — | — | EP | disclosed |
| WO-2012167081-A1 | HYDRAZINO 1H-IMIDAZOQUINOLIN-4-AMINES AND CONJUGATES MADE THEREFROM | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-12-06 | — | — | WO | disclosed |
| EP-2102175-A1 | TRIAZOLE DERIVATIVE AS AN HSP 90 INHIBITOR | Merck Patent GmbH (DE) | 2009-09-23 | — | — | EP | disclosed |
| CN-101426792-A | Pyrazolopyrimidines as therapeutic agents | ABBOTT GMBH & CO KG (DE) | 2009-05-06 | — | — | CN | disclosed |
| WO-2008086857-A1 | TRIAZOLE DERIVATIVE AS AN HSP 90 INHIBITOR | MERCK PATENT GMBH (DE) | 2008-07-24 | — | — | WO | disclosed |
| EP-1853570-A2 | HSP90-INHIBITING TRIAZOLE DERIVATIVES | Merck Patent GmbH (DE) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006087077-A2 | HSP90-INHIBITING TRIAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2006-08-24 | — | — | WO | disclosed |
| US-4262113-A | INTERFACIAL POLYMERIZATION TO FORM HIGH MOLECULAR WEIGHT AROMATIC POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 1981-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140286988-A1 | HYDRAZINO 1H-IMIDAZOQUINOLIN-4-AMINES AND CONJUGATES MADE THEREFROM | IL15, IL2, HNMT | KMT2A 423/4885MEN1 3424/4885POLB 3773/4885 |
| US-20170173164-A1 | HYDRAZINO 1H-IMIDAZOQUINOLIN-4-AMINES AND CONJUGATES MADE THEREFROM | IL15, IL2, HNMT | KMT2A 423/4885MEN1 3424/4885POLB 3773/4885 |
| US-10406142-B2 | Hydrazino 1H-imidazoquinolin-4-amines and conjugates made therefrom | IL15, IL2, HNMT | KMT2A 423/4885MEN1 3424/4885POLB 3773/4885 |
| US-20150352218-A1 | HYDRAZINO 1H-IMIDAZOQUINOLIN-4-AMINES AND CONJUGATES MADE THEREFROM | IL15, IL2, HNMT | KMT2A 423/4885MEN1 3424/4885POLB 3773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.