Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.51 |
| ▸ | ITGAV | P06756 | 12/20 | 0.51 |
| ▸ | MMP2 | P08253 | 5/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.39 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.39 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382203 | 0.92 | ITGB3 (0.57) | ITGB3ITGA2BITGAV | |
| SCHEMBL382475 | 0.92 | ITGB3 (0.43) | ITGB3ITGA2BITGAVMMP2MMP9 | |
| SCHEMBL382290 | 0.91 | ITGB3 (0.57) | ITGB3ITGA2BITGAV | |
| SCHEMBL381745 | 0.90 | ITGB3 (0.59) | ITGB3ITGA2BITGAV | |
| SCHEMBL382306 | 0.88 | ITGB3 (0.65) | ITGB3ITGA2BITGAV | |
| SCHEMBL382874 | 0.86 | ITGB3 (0.38) | ITGB3ITGA2BITGAVMMP2MMP9 | |
| SCHEMBL6499610 | 0.86 | ITGB3 (0.55) | ITGB3ITGA2BITGAV | |
| SCHEMBL383234 | 0.85 | ITGB3 (0.69) | ITGB3ITGA2BITGAV | |
| SCHEMBL382801 | 0.84 | ITGAV (0.46) | ITGB3ITGA2BITGAV | |
| SCHEMBL7474804 | 0.83 | ITGB3 (0.60) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |
| EP-1074543-A1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2001-02-07 | — | — | EP | claimed |
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |
| EP-1074543-A1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2001-02-07 | — | — | EP | disclosed |