SCHEMBL3828889

SCHEMBL3828889

Oc1cc2cc[nH]c2cn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.50
GAA P10253 1/20 0.50
ALOX15 P16050 1/20 0.50
RAD51 Q06609 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
HDAC6 Q9UBN7 1/20 0.46
TYR P14679 1/20 0.45
MAPT P10636 1/20 0.43
MAOB P27338 4/20 0.42
GPR84 Q9NQS5 1/20 0.42
AHR P35869 3/20 0.41
NR4A2 P43354 2/20 0.41
CYP2A6 P11509 1/20 0.41
F7 P08709 1/20 0.41
LTA4H P09960 1/20 0.41
F3 P13726 1/20 0.41
GRM4 Q14833 1/20 0.40
RIPK1 Q13546 1/20 0.40
F2 P00734 1/20 0.39
DYRK1A Q13627 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30354467 1.00 USP2 (0.50) USP2GAAALOX15RAD51NPSR1
Hydrochloric Acid SCHEMBL3824712 0.98 USP2 (0.48) USP2GAAALOX15RAD51NPSR1
SCHEMBL28482610 0.83 TYR (0.50) USP2GAAALOX15RAD51NPSR1
SCHEMBL21090062 0.79 HDAC6 (0.43) USP2GAAALOX15RAD51NPSR1
SCHEMBL3831376 0.76 IMPDH2 (0.52) USP2GAAALOX15RAD51NPSR1
SCHEMBL30088200 0.76 IMPDH2 (0.52) USP2GAAALOX15RAD51NPSR1
SCHEMBL13778764 0.76 HDAC6 (0.48) USP2GAAALOX15RAD51NPSR1
SCHEMBL8664673 0.75 PDPK1 (0.47) USP2GAAALOX15RAD51NPSR1
SCHEMBL587359 0.75 AHR (0.50) USP2GAAALOX15RAD51NPSR1
SCHEMBL8296659 0.75 CYP2A6 (0.47) USP2GAAALOX15RAD51NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1784404-A4 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2009-09-09 EP claimed
JP-2008511621-A 2008-04-17 JP claimed
EP-1784404-A1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF Yuhan Corporation (KR) 2007-05-16 EP claimed
WO-2006025716-A1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO claimed
EP-4635954-A1 INDUCER FOR INDUCING MESENCHYMAL-EPITHELIAL TRANSITION AND REPROGRAMMING Iregene Therapeutics Co., Ltd (CN) 2025-10-22 EP disclosed
EP-4611743-A1 TRIAZINES USEFUL AS INHIBITORS OF NOD-LIKE RECEPTOR PROTEIN 3 Merck Sharp & Dohme LLC (US) 2025-09-10 EP disclosed
WO-2024124464-A1 INDUCER FOR INDUCING MESENCHYMAL-EPITHELIAL TRANSITION AND REPROGRAMMING 武汉睿健医药科技有限公司 2024-06-20 WO disclosed
WO-2024124464-A1 INDUCER FOR INDUCING MESENCHYMAL-EPITHELIAL TRANSITION AND REPROGRAMMING 武汉睿健医药科技有限公司 2024-06-20 WO disclosed
WO-2024124463-A1 PYRROLOPYRIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 武汉睿健医药科技有限公司 2024-06-20 WO disclosed
WO-2024124463-A1 PYRROLOPYRIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 武汉睿健医药科技有限公司 2024-06-20 WO disclosed
WO-2024097598-A1 TRIAZINES USEFUL AS INHIBITORS OF NOD-LIKE RECEPTOR PROTEIN 3 MERCK SHARP & DOHME LLC (US) 2024-05-10 WO disclosed
US-20200131176-A1 SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE CS PHARMATECH LIMITED (KY) 2020-04-30 US disclosed
US-20190177317-A1 PROCESS FOR THE PREPARATION OF VENETOCLAX MYLAN LABORATORIES LIMITED (IN) 2019-06-13 US disclosed
US-9174982-B2 Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases ABBVIE INC. (US) 2015-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190177317-A1 PROCESS FOR THE PREPARATION OF VENETOCLAX MCL1, RTCB, VAV1 USP2 2605/4885GAA 1448/4885ALOX15 2771/4885
US-20200131176-A1 SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE EGFR, ERBB3, ERBB2 USP2 2060/4885GAA 1620/4885ALOX15 4863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.