SCHEMBL3829239

SCHEMBL3829239

O=[C]N(c1ccccc1)S(=O)(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 2/20 0.38
ESR1 P03372 3/20 0.37
HSP90AA1 P07900 2/20 0.37
PKM P14618 1/20 0.35
ALDH1A1 P00352 4/20 0.33
CA12 O43570 2/20 0.33
CA9 Q16790 2/20 0.33
HTT P42858 2/20 0.33
CA2 P00918 1/20 0.33
HPGD P15428 1/20 0.33
XBP1 P17861 1/20 0.33
ALOX12 P18054 1/20 0.33
RUNX1 Q01196 1/20 0.33
ATM Q13315 1/20 0.33
CBFB Q13951 1/20 0.33
ALOX15 P16050 1/20 0.33
KMT2A Q03164 2/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11823087 0.79 MAPT (0.41) TSHRSMN1; SMN2ALDH1A1CA12CA9
SCHEMBL6950233 0.78 NR3C2 (0.39) TSHRSMN1; SMN2NPSR1ESR1HSP90AA1
SCHEMBL1751506 0.78 CA2 (0.41) NPSR1ESR1HSP90AA1PKMALDH1A1
SCHEMBL313109 0.72 TSHR (0.46) TSHRSMN1; SMN2NPSR1ESR1HSP90AA1
SCHEMBL450584 0.72 ESR1 (0.52) TSHRSMN1; SMN2NPSR1ESR1HSP90AA1
SCHEMBL3241706 0.71 ESR1 (0.46) TSHRSMN1; SMN2NPSR1ESR1HSP90AA1
SCHEMBL11322994 0.70 ESR1 (0.50) TSHRSMN1; SMN2NPSR1ESR1HSP90AA1
SCHEMBL378351 0.70 ESR1 (0.50) TSHRSMN1; SMN2NPSR1ESR1HSP90AA1
SCHEMBL11308673 0.70 ESR1 (0.50) TSHRSMN1; SMN2NPSR1ESR1HSP90AA1
SCHEMBL415688 0.70 ESR1 (0.50) TSHRSMN1; SMN2NPSR1ESR1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1930162-B Tetrahydropyridoindole derivatives ACTELION PHARMACEUTICALS LTD 2010-06-16 CN claimed
CN-1930162-A Tetrahydropyridoindole derivatives ACTELION PHARMACEUTICALS LTD (CH) 2007-03-14 CN claimed
US-4138260-A Photographic film unit with crosslinked neutralization layer AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1979-02-06 US claimed
US-20230150951-A1 2,5- OR 2,6-DISUBSTITUTED HYDROQUINONE DERIVATIVES WITH AT LEAST ONE CARBOXY, SULFO OR AMIDO GROUP USEFUL AS MEDICAMENTS OM PHARMA SA (CH) 2023-05-18 US disclosed
EP-1522559-B1 WATER-SOLUBLE COMPLEX DYE, RECORDING FLUID, AND METHOD OF RECORDING MITSUBISHI CHEM CORP (JP) 2009-09-16 EP disclosed
CN-100372895-C Water-soluble complex dye, recording fluid and recording method MITSUBISHI CHEM CORP (JP) 2008-03-05 CN disclosed
US-7097700-B2 Water-soluble complex dye, recording fluid and recording method MITSUBISHI CHEMICAL CORPORATION (JP) 2006-08-29 US disclosed
US-7094280-B2 Water-soluble complex dye, recording fluid and recording method MITSUBISHI CHEMICAL CORPORATION (JP) 2006-08-22 US disclosed
US-7025815-B2 Water-soluble complex dye, recording fluid and recording method MITSUBISHI CHEMICAL CORPORATION (JP) 2006-04-11 US disclosed
CN-1668706-A Water-soluble complex dye, recording fluid and recording method MITSUBISHI CHEM CORP (JP) 2005-09-14 CN disclosed
US-20050109237-A1 Water-soluble complex dye, recording fluid and recording method MITSUBISHI CHEMICAL CORPORATION (JP) 2005-05-26 US disclosed
EP-1522559-A1 WATER-SOLUBLE COMPLEX DYE, RECORDING FLUID, AND METHOD OF RECORDING Mitsubishi Chemical Corporation (JP) 2005-04-13 EP disclosed
EP-1522558-A1 WATER-SOLUBLE COMPLEX DYE, RECORDING FLUID, AND METHOD OF RECORDING Mitsubishi Chemical Corporation (JP) 2005-04-13 EP disclosed
EP-0593177-B1 Silver halide photographic emulsion and light-sensitive silver halide photographic material KONISHIROKU PHOTO IND (JP) 1998-07-15 EP disclosed
EP-0447137-B1 Light-sensitive silver halide photographic material KONISHIROKU PHOTO IND (JP) 1995-09-13 EP disclosed
US-5403705-A Optically sensitized by addition of dispersion of particles of optical sensitizer; storage stability KONICA CORPORATION (JP) 1995-04-04 US disclosed
EP-0593177-A1 Silver halide photographic emulsion and light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1994-04-20 EP disclosed
US-5204232-A Optical stability; antisoilants; aging resistance; color photography KONICA CORPORATION (JP) 1993-04-20 US disclosed
EP-0447137-A1 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1991-09-18 EP disclosed
US-3979378-A Water-soluble azo dyes having a substituted 2-hydroxypyridone (6) coupling component BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150951-A1 2,5- OR 2,6-DISUBSTITUTED HYDROQUINONE DERIVATIVES WITH AT LEAST ONE CARBOXY, SULFO OR AMIDO GROUP USEFUL AS MEDICAMENTS HRH4, NCOA4, HRH3 TSHR 1884/4885SMN1; SMN2 524/4885NPSR1 663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.