Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2399859 | 0.89 | KDM1A (0.67) | KDM1AHDAC1HDAC6NAPRTKMT2A | |
| SCHEMBL2399857 | 0.89 | KDM1A (0.67) | KDM1AHDAC1HDAC6NAPRTKMT2A | |
| Hydrochloric Acid SCHEMBL6706505 | 0.88 | KDM1A (0.65) | KDM1AHDAC1HDAC6NAPRTKMT2A | |
| Hydrochloric Acid SCHEMBL6706503 | 0.88 | KDM1A (0.65) | KDM1AHDAC1HDAC6NAPRTKMT2A | |
| SCHEMBL14856712 | 0.84 | HDAC1 (0.50) | HDAC1NAPRTKMT2ANPC1RAB9A | |
| SCHEMBL3810923 | 0.84 | MAPT (0.69) | KDM1AHDAC1HDAC6KMT2ANPC1 | |
| SCHEMBL4410983 | 0.84 | MAPT (0.69) | KDM1AHDAC1HDAC6KMT2ANPC1 | |
| SCHEMBL4411642 | 0.81 | KDM1A (0.54) | KDM1AHDAC1HDAC6KMT2ANPC1 | |
| SCHEMBL28452789 | 0.81 | NAPRT (0.57) | HDAC1HDAC6NAPRTMAPTSMN1; SMN2 | |
| SCHEMBL22170316 | 0.80 | MAPT (0.60) | KDM1AHDAC1HDAC6KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086937-A1 | NOVEL TRIPHENYLAMINE DERIVATIVES FOR USE AS FLUOROPHORES IN BIOLOGY, IN PARTICULAR FOR TWO-PHOTON MICROSCOPY | Commissariat à l'Energie Atomique (FR) | 2009-08-12 | — | — | EP | claimed |
| WO-2008055969-A1 | NOVEL TRIPHENYLAMINE DERIVATIVES FOR USE AS FLUOROPHORES IN BIOLOGY, IN PARTICULAR FOR TWO-PHOTON MICROSCOPY | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-05-15 | — | — | WO | claimed |
| EP-2086937-A1 | NOVEL TRIPHENYLAMINE DERIVATIVES FOR USE AS FLUOROPHORES IN BIOLOGY, IN PARTICULAR FOR TWO-PHOTON MICROSCOPY | Commissariat à l'Energie Atomique (FR) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008055969-A1 | NOVEL TRIPHENYLAMINE DERIVATIVES FOR USE AS FLUOROPHORES IN BIOLOGY, IN PARTICULAR FOR TWO-PHOTON MICROSCOPY | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-05-15 | — | — | WO | disclosed |