Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | HBB | P68871 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981695 | 0.91 | KDM1A (0.64) | KDM1AHDAC1HDAC6PTPN1SNCA | |
| SCHEMBL7975552 | 0.91 | KDM1A (0.64) | KDM1AHDAC1HDAC6PTPN1SNCA | |
| SCHEMBL7975551 | 0.91 | KDM1A (0.64) | KDM1AHDAC1HDAC6PTPN1SNCA | |
| SCHEMBL19076177 | 0.84 | ALDH1A1 (0.56) | KDM1AHDAC1HDAC6PTPN1SNCA | |
| SCHEMBL3829376 | 0.81 | KDM1A (0.56) | KDM1AHDAC1HDAC6SNCAMAPT | |
| SCHEMBL31301140 | 0.80 | PTPN1 (0.73) | PTPN1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL71401 | 0.80 | PTPN1 (0.73) | PTPN1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL2627847 | 0.80 | PTPN1 (0.73) | PTPN1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL71402 | 0.80 | PTPN1 (0.73) | PTPN1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL5379059 | 0.80 | PTPN1 (0.73) | PTPN1MAPTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8664400-B2 | Triphenylamine derivatives useful as fluorophores in biology, in particular for two-photon microscopy | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-03-04 | — | — | US | claimed |
| US-20090314990-A1 | NOVEL TRIPHENYLAMINE DERIVATIVES USEFUL AS FLUOROPHORES IN BIOLOGY, IN PARTICULAR FOR TWO-PHOTON MICROSCOPY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-12-24 | — | — | US | claimed |
| US-8664400-B2 | Triphenylamine derivatives useful as fluorophores in biology, in particular for two-photon microscopy | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-03-04 | — | — | US | disclosed |
| US-20090314990-A1 | NOVEL TRIPHENYLAMINE DERIVATIVES USEFUL AS FLUOROPHORES IN BIOLOGY, IN PARTICULAR FOR TWO-PHOTON MICROSCOPY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090314990-A1 | NOVEL TRIPHENYLAMINE DERIVATIVES USEFUL AS FLUOROPHORES IN BIOLOGY, IN PARTICULAR FOR TWO-PHOTON MICROSCOPY | TERB1, TRDMT1, TARBP1 | KDM1A 4129/4885HDAC1 3732/4885HDAC6 2165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.