Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27684259 | 0.86 | FGFR1 (0.42) | FGFR1FGFR4PDE4APDE4BPDE4C | |
| SCHEMBL3015481 | 0.81 | FGFR1 (0.46) | FGFR1FGFR4PDE4APDE4BPDE4C | |
| SCHEMBL2748776 | 0.79 | FGFR1 (0.40) | FGFR1FGFR4PDE4APDE4BPDE4C | |
| SCHEMBL2747871 | 0.77 | FGFR1 (0.41) | FGFR1FGFR4 | |
| SCHEMBL3506358 | 0.77 | FGFR1 (0.39) | FGFR1FGFR4PDE4APDE4BPDE4C | |
| SCHEMBL3484536 | 0.77 | FGFR1 (0.38) | FGFR1FGFR4PDE4APDE4BPDE4C | |
| SCHEMBL3400734 | 0.77 | FGFR1 (0.39) | FGFR1FGFR4 | |
| SCHEMBL2749112 | 0.76 | FGFR1 (0.53) | FGFR1FGFR4PDE4APDE4BPDE4C | |
| SCHEMBL3509903 | 0.76 | FGFR1 (0.38) | FGFR1FGFR4PDE4APDE4BPDE4C | |
| SCHEMBL4289543 | 0.76 | FGFR1 (0.45) | FGFR1FGFR4PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1993362-B | Fused Heterocyclic Compounds | TAKEDA PHARMACEUTICAL | 2010-12-15 | — | — | CN | disclosed |
| EP-2103620-A1 | FUSED HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-09-23 | — | — | EP | disclosed |
| EP-1957495-A1 | FUSED HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| CN-1993362-A | Fused Heterocyclic Compounds | TAKEDA PHARMACEUTICAL (JP) | 2007-07-04 | — | — | CN | disclosed |
| WO-2007064045-A1 | FUSED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |