Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.89 |
| ▸ | MAPT | P10636 | 3/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.89 |
| ▸ | LMNA | P02545 | 2/20 | 0.89 |
| ▸ | TSHR | P16473 | 2/20 | 0.89 |
| ▸ | BLM | P54132 | 2/20 | 0.89 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.89 |
| ▸ | MEN1 | O00255 | 2/20 | 0.89 |
| ▸ | MPO | P05164 | 1/20 | 0.89 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.89 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | APAF1 | O14727 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 3/20 | 0.61 |
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | HTR2C | P28335 | 2/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | HTR7 | P34969 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tryptophan SCHEMBL3831274 | 1.00 | KDM4E (0.89) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL27327550 | 0.94 | KDM4E (0.89) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL27840618 | 0.94 | KDM4E (0.89) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL7327 | 0.94 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL475350 | 0.94 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL23141133 | 0.94 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL4732052 | 0.94 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL475349 | 0.94 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL289042 | 0.94 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL4732053 | 0.94 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116200374-B | D-carbamoyl hydrolase mutant with improved thermal stability and application thereof in synthesis of D-amino acid | 江南大学 | 2025-06-17 | — | — | CN | disclosed |
| CN-116200374-B | D-carbamoyl hydrolase mutant with improved thermal stability and application thereof in synthesis of D-amino acid | 江南大学 | 2025-06-17 | — | — | CN | disclosed |
| CN-116200374-A | D-carbamoyl hydrolase mutant with improved thermal stability and application thereof in synthesis of D-amino acid | 江南大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-116200374-A | D-carbamoyl hydrolase mutant with improved thermal stability and application thereof in synthesis of D-amino acid | 江南大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-109468304-B | Hydantoinase mutants | 赢创运营有限公司 | 2022-04-19 | — | — | CN | disclosed |
| US-10822627-B2 | Mutants of hydantoinase | EVONIK OPERATIONS GMBH (DE) | 2020-11-03 | — | — | US | disclosed |
| US-20180237814-A1 | MUTANTS OF HYDANTOINASE | EVONIK TECHNOCHEMIE GMBH (DE) | 2018-08-23 | — | — | US | disclosed |
| US-9957536-B2 | Mutants of hydantoinase | EVONIK TECHNOCHEMIE GMBH (DE) | 2018-05-01 | — | — | US | disclosed |
| EP-2780451-B1 | MUTANTS OF HYDANTOINASE | EVONIK TECHNOCHEMIE GMBH (DE) | 2017-09-20 | — | — | EP | disclosed |
| US-20150056667-A1 | MUTANTS OF HYDANTOINASE | EVONIK OPERATIONS GMBH (DE) | 2015-02-26 | — | — | US | disclosed |
| EP-2780451-A1 | MUTANTS OF HYDANTOINASE | Evonik Industries AG (DE) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013072486-A1 | MUTANTS OF HYDANTOINASE | EVONIK INDUSTRIES AG (DE) | 2013-05-23 | — | — | WO | disclosed |
| EP-1070132-B1 | RECOMBINANT L-N-CARBAMOYLASE DERIVED FROM ARTHROBACTER AURESCENS, AND A METHOD FOR PRODUCING L-AMINO ACIDS BY USING THE SAME | EVONIK DEGUSSA GMBH (DE) | 2009-09-23 | — | — | EP | disclosed |
| US-5916781-A | COMPRISES CONTACTING D,L-TRYPTOPHAN MIXTURE WITH TRYPTOPHANASE, MICROORGANISM PRODUCING TRYPTOPHANASE, OR TREATED PRODUCT OF MICROORGANISM PRODUCING TRYPTOPHANASE TO SELECTIVELY DEGRADE L-TRYPTOPHAN, THEREBY INCREASING CONTENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-06-29 | — | — | US | disclosed |
| EP-0853128-A1 | Method for producing D-tryptophan | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-07-15 | — | — | EP | disclosed |