Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GPX4 | P36969 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744537 | 0.89 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTMEN1KMT2AHTT | |
| SCHEMBL6632512 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2MAPTMEN1KMT2AHTT | |
| SCHEMBL902 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTGAANPC1ALDH1A1 | |
| SCHEMBL27596057 | 0.83 | KDM4C (0.43) | SMN1; SMN2MAPTMEN1KMT2AHTT | |
| SCHEMBL1070 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTGAAALDH1A1CASP7 | |
| Methane SCHEMBL28911261 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTGAAALDH1A1CASP7 | |
| SCHEMBL11327068 | 0.82 | HTT (0.39) | SMN1; SMN2MAPTMEN1KMT2AHTT | |
| SCHEMBL6446674 | 0.81 | CYP1A2 (0.52) | SMN1; SMN2MEN1KMT2ANPC1LMNA | |
| SCHEMBL8187253 | 0.78 | MAPT (0.39) | SMN1; SMN2MAPTMEN1KMT2AGAA | |
| SCHEMBL3827995 | 0.76 | GLA (0.37) | SMN1; SMN2MAPTPARP1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1793828-A4 | FIBRATE COMPOUNDS HAVING PPAR AGONIST ACTIVITY | REDDYS LAB LTD DR (IN) | 2009-09-02 | — | — | EP | disclosed |
| EP-1793828-A2 | FIBRATE COMPOUNDS HAVING PPAR AGONIST ACTIVITY | Dr. Reddy's Laboratories Ltd. (IN) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006029075-A2 | FIBRATE COMPOUNDS HAVING PPAR AGONIST ACTIVITY | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-03-16 | — | — | WO | disclosed |