SCHEMBL383081

SCHEMBL383081

O=C(O)C(CO)C(Cl)(Cl)Cl

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.39
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
PDE4A P27815 1/20 0.32
SLC1A1 P43005 1/20 0.31
USP2 O75604 1/20 0.30
SLCO1B1 Q9Y6L6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1591295 0.76 TDP1 (0.43) ALDH1A1LMNATP53TSHR
SCHEMBL1318048 0.76 CYP2C19 (0.32)
SCHEMBL315108 0.76 CHRM1 (0.35) ALDH1A1LMNATP53TSHRSLC1A1
SCHEMBL3369501 0.72 OR51E2 (0.39) OR51E2PDE4ASLC1A1USP2SLCO1B1
SCHEMBL13316605 0.72 OR51E2 (0.39) OR51E2ALDH1A1TP53TSHRPDE4A
SCHEMBL3368128 0.72 OR51E2 (0.39) OR51E2ALDH1A1TSHRPDE4ASLC1A1
SCHEMBL667279 0.72 OR51E2 (0.39) OR51E2ALDH1A1TP53TSHRPDE4A
SCHEMBL5688214 0.72 OR51E2 (0.39) OR51E2PDE4ASLC1A1USP2SLCO1B1
SCHEMBL1234369 0.72 OR51E2 (0.39) OR51E2PDE4ASLC1A1USP2SLCO1B1
SCHEMBL1591739 0.72 ALDH1A1 (0.40) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 716 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110967441-B Rapid thin-layer identification method for Jinshi Liyan granules 河北中医学院 2021-07-02 CN claimed
WO-2021128807-A1 RAPID THIN-LAYER IDENTIFICATION METHOD OF RADIX PUERARIAE INTESTINE-CLEARING GRANULES 河北中医学院 2021-07-01 WO claimed
CN-110988248-B Rapid thin-layer identification method for radix puerariae intestine clearing granules 河北中医学院 2021-06-18 CN claimed
CN-110988248-A Rapid thin-layer identification method for radix puerariae intestine clearing granules 河北中医学院 2020-04-10 CN claimed
CN-110967441-A Rapid thin-layer identification method for Jinshi Liyan granules 河北中医学院 2020-04-07 CN claimed
CN-110123865-A Composition comprising man and wife's grass extract 嘉兴市爵拓科技有限公司 2019-08-16 CN claimed
CN-107253955-B The preparation method and its usage of pyrans a pair of horses going side by side benzazolyl compounds 上海海洋大学 2019-04-16 CN claimed
CN-107253955-A The preparation method and its usage of pyrans a pair of horses going side by side benzazolyl compounds 上海海洋大学 2017-10-17 CN claimed
CN-105319333-B Quality detection method for Jingxuening capsule 广西中医药大学 2017-04-26 CN claimed
CN-105319333-A Quality detection method for Jingxuening capsule UNIV GUANGXI CHINESE MEDICINE 2016-02-10 CN claimed
CN-102085322-B Detection method of traditional Chinese medicine composition for treating hematuria BEIJING ASIA EAST BIO PHARM CO 2012-12-05 CN claimed
CN-102503826-A Compound Blapsins A and B, pharmaceutical composition containing the same, and preparation method and application thereof KUNMING INST BOTANY CN ACAD 2012-06-20 CN claimed
CN-102085322-A Detection method of traditional Chinese medicine composition for treating hematuria BEIJING ASIA EAST BIO PHARM CO 2011-06-08 CN claimed
CN-101288753-B Traditional Chinese medicine composition for treating hematuria and preparation method and detection method thereof BEIJING ASIA EAST BIO PHARM CO 2011-02-09 CN claimed
CN-101199812-B Chinese medicine granules for treating heart function exhaustion, producing method and quality controlling method thereof Shandong buchang pharmaceutical co ltd 2010-10-27 CN claimed
CN-101288753-A A Chinese medicinal composition for treating hematuria, and its preparation method and quality control method BEIJING ASIA EAST BIO PHARM CO (CN) 2008-10-22 CN claimed
CN-101199812-A Chinese medicine granules for treating heart function exhaustion, producing method and quality controlling method thereof XIANYANG BUCHANG MEDICINE SCIE (CN) 2008-06-18 CN claimed
US-4420473-A ANTHRACYCLINE, BACTERICIDES ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1983-12-13 US claimed
EP-0048660-B1 NEW ANTIBIOTIC SUBSTANCE, ITS PROCESS OF PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1983-10-12 EP claimed
EP-0048660-A1 New antibiotic substance, its process of production and pharmaceutical composition containing the same ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1982-03-31 EP claimed