Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9141562 | 0.81 | TTR (0.39) | TTRPOLBNLRP3 | |
| SCHEMBL25477911 | 0.78 | CA12 (0.45) | TTRPOLBCA1CA2CA9 | |
| SCHEMBL9555635 | 0.77 | TSHR (0.42) | CA1CA2CA9 | |
| SCHEMBL5682568 | 0.73 | — | — | |
| SCHEMBL10498088 | 0.71 | TTR (0.50) | TTRPOLBNLRP3 | |
| SCHEMBL8337136 | 0.70 | TTR (0.31) | TTR | |
| SCHEMBL8203344 | 0.69 | NR1H2 (0.53) | CA1CA2CA9 | |
| SCHEMBL23601630 | 0.69 | ESR1 (0.39) | TTR | |
| SCHEMBL13479795 | 0.68 | MAPK1 (0.38) | CA1CA2 | |
| SCHEMBL27788856 | 0.67 | TTR (0.31) | TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804162-A1 | BUTYLENE OXIDE-ETHYLENE OXIDE BLOCK COPOLYMER SURFACTANTS AS STABILIZER COATINGS FOR NANOCRYSTAL FORMULATION | NanoSystems L.L.C. (US) | 1997-11-05 | — | — | EP | claimed |
| EP-0767779-A1 | ALPHA-(CYCLOALKYL, ARYL AND ARALKYL)SUBSTITUTED POLYIODINATED AROYLOXY COMPOUNDS | NanoSystems L.L.C. (US) | 1997-04-16 | — | — | EP | claimed |
| EP-0749414-A1 | IODINATED AROYLOXY KETONES | NanoSystems L.L.C. (US) | 1996-12-27 | — | — | EP | claimed |
| WO-1996022766-A1 | SULFATED NONIONIC BLOCK COPOLYMER SURFACTANTS AS STABILIZER COATINGS FOR NANOPARTICLE COMPOSITIONS | NANOSYSTEMS L.L.C. (US) | 1996-08-01 | — | — | WO | claimed |
| WO-1996000567-A1 | BUTYLENE OXIDE-ETHYLENE OXIDE BLOCK COPOLYMER SURFACTANTS AS STABILIZER COATINGS FOR NANOCRYSTAL FORMULATION | NANOSYSTEMS L.L.C. (US) | 1996-01-11 | — | — | WO | claimed |
| WO-1996000211-A1 | ALPHA-(CYCLOALKYL, ARYL AND ARALKYL)SUBSTITUTED POLYIODINATED AROYLOXY COMPOUNDS | NANOSYSTEMS L.L.C. (US) | 1996-01-04 | — | — | WO | claimed |
| US-5429824-A | Use of tyloxapole as a nanoparticle stabilizer and dispersant | EASTMAN KODAK COMPANY (US) | 1995-07-04 | — | — | US | claimed |
| CN-101188996-B | Surface-modified microparticles and methods of forming and using the same | BAXTER INT | 2013-03-27 | — | — | CN | disclosed |
| EP-2125054-A2 | PARTIALLY BIOABSORBABLE IMPLANT | CINVENTION AG (DE) | 2009-12-02 | — | — | EP | disclosed |
| EP-2120807-A2 | DEGRADABLE RESERVOIR IMPLANTS | CINVENTION AG (DE) | 2009-11-25 | — | — | EP | disclosed |
| EP-2117613-A1 | CARBON STENTS | CINVENTION AG (DE) | 2009-11-18 | — | — | EP | disclosed |
| EP-2111193-A1 | RESERVOIR IMPLANTS AND STENTS | CINVENTION AG (DE) | 2009-10-28 | — | — | EP | disclosed |
| EP-2111482-A2 | MEDICAL DEVICES WITH EXTENDED OR MULTIPLE RESERVOIRS | CINVENTION AG (DE) | 2009-10-28 | — | — | EP | disclosed |
| WO-1995022995-A1 | X-RAY CONTRAST COMPOSITIONS CONTAINING CELLULOSE DERIVATIVES | NYCOMED IMAGING A/S (NO) | 1995-08-31 | — | — | WO | disclosed |
| US-5429824-A | Use of tyloxapole as a nanoparticle stabilizer and dispersant | EASTMAN KODAK COMPANY (US) | 1995-07-04 | — | — | US | disclosed |
| US-5416223-A | Iodinated esters | NYCOMED IMAGING AS (NO) | 1995-05-16 | — | — | US | disclosed |
| US-5384107-A | X-RAY CONTRAST COMPOSITIONS | STERLING WINTHROP INC. (US) | 1995-01-24 | — | — | US | disclosed |
| US-5318767-A | X-ray contrast compositions useful in medical imaging | STERLING WINTHROP INC. (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0452377-A1 | IODINATED ESTERS. | HOLMES MICHAEL JOHN (GB) | 1991-10-23 | — | — | EP | disclosed |
| WO-1990007491-A1 | IODINATED ESTERS | NYCOMED AS (NO) | 1990-07-12 | — | — | WO | disclosed |