SCHEMBL8337136

SCHEMBL8337136

CC(=O)NC(OC(=O)c1c(I)cc(I)cc1I)(C(=O)O)C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TTR P02766 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5682568 0.78 — —
SCHEMBL23559562 0.71 TTR (0.31) TTR
SCHEMBL25477911 0.70 CA12 (0.45) TTR
SCHEMBL3831246 0.70 TTR (0.37) TTR
SCHEMBL9141562 0.66 TTR (0.39) TTR
SCHEMBL10498088 0.64 TTR (0.50) TTR
SCHEMBL8203344 0.63 NR1H2 (0.53) —
SCHEMBL23559290 0.62 GABRA1 (0.32) —
SCHEMBL23601630 0.62 ESR1 (0.39) TTR
SCHEMBL23559265 0.62 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0810855-A4 POLYALKYLENE BLOCK COPOLYMERS AS SURFACE MODIFIERS FOR NANOPARTICLES NANOSYSTEMS LLC (US) 1999-04-07 — — EP disclosed
EP-0810855-A1 POLYALKYLENE BLOCK COPOLYMERS AS SURFACE MODIFIERS FOR NANOPARTICLES NanoSystems L.L.C. (US) 1997-12-10 — — EP disclosed
WO-1996025921-A1 POLYALKYLENE BLOCK COPOLYMERS AS SURFACE MODIFIERS FOR NANOPARTICLES NANOSYSTEMS L.L.C. (US) 1996-08-29 — — WO disclosed
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