Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3831258 | 1.00 | HSD17B10 (0.47) | HSD17B10HTR2CRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3829823 | 0.89 | HSD17B10 (0.48) | HSD17B10HTR2CGAAFFAR2GRIN2B | |
| SCHEMBL3830117 | 0.89 | HSD17B10 (0.48) | HSD17B10HTR2CGAAFFAR2GRIN2B | |
| SCHEMBL3826029 | 0.89 | HSD17B10 (0.48) | HSD17B10HTR2CGAAFFAR2GRIN2B | |
| SCHEMBL3831329 | 0.88 | HSD17B10 (0.59) | HSD17B10HTR2CRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3831328 | 0.88 | HSD17B10 (0.59) | HSD17B10HTR2CRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3832317 | 0.88 | HSD17B10 (0.51) | HSD17B10HTR2CRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3225960 | 0.88 | HSD17B10 (0.51) | HSD17B10HTR2CRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3828037 | 0.83 | HSD17B10 (0.51) | HSD17B10HTR2CRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3828033 | 0.83 | HSD17B10 (0.51) | HSD17B10HTR2CRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099778-A2 | AMIDO ANTI-VIRAL COMPOUNDS | Smithkline Beecham Corporation (US) | 2009-09-16 | — | — | EP | disclosed |
| US-20080181866-A1 | Amido Anti-viral Compounds | GENELABS TECHNOLOGIES, INC. | 2008-07-31 | — | — | US | disclosed |
| WO-2008064218-A2 | AMIDO ANTI-VIRAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080181866-A1 | Amido Anti-viral Compounds | ZC3HAV1, U2SURP, ZC3HAV1L | HSD17B10 4331/4885HTR2C 3911/4885RAB9A 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.