⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3831335 | 1.00 | — | — | |
| SCHEMBL12994146 | 1.00 | — | — | |
| SCHEMBL13588926 | 0.92 | — | — | |
| SCHEMBL1841924 | 0.92 | — | — | |
| SCHEMBL1841927 | 0.92 | — | — | |
| SCHEMBL20148133 | 0.89 | — | — | |
| SCHEMBL19036886 | 0.84 | ALDH1A1 (0.30) | — | |
| SCHEMBL18269422 | 0.77 | HCAR2 (0.32) | — | |
| SCHEMBL5316360 | 0.76 | ALDH1A1 (0.32) | — | |
| SCHEMBL5316362 | 0.76 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091923-A1 | PROCESS FOR THE PREPARATION OF ROSUVASTATIN | AstraZeneca UK Limited (GB) | 2009-08-26 | — | — | EP | disclosed |
| US-20080188657-A1 | CHEMICAL PROCESS | ASTRAZENECA UK LIMITED (GB) | 2008-08-07 | — | — | US | disclosed |
| WO-2008065410-A1 | PROCESS FOR THE PREPARATION OF ROSUVASTATIN | ASTRAZENECA UK LIMITED (GB) | 2008-06-05 | — | — | WO | disclosed |