Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCK | P27707 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312504 | 0.78 | DCK (0.49) | DCK | |
| SCHEMBL10172488 | 0.65 | DCK (0.53) | DCK | |
| SCHEMBL10172442 | 0.65 | DCK (0.48) | DCK | |
| SCHEMBL311117 | 0.65 | DCK (0.51) | DCK | |
| SCHEMBL13530550 | 0.65 | DCK (0.48) | DCK | |
| SCHEMBL311256 | 0.64 | DCK (0.73) | DCK | |
| SCHEMBL10172453 | 0.63 | DCK (0.48) | DCK | |
| SCHEMBL312481 | 0.63 | DCK (0.47) | DCK | |
| SCHEMBL10172476 | 0.62 | DCK (0.86) | DCK | |
| SCHEMBL10172500 | 0.62 | DCK (0.47) | DCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2104672-A2 | 2-(PIPERIDIN-4-YL0XY)PYRIMIDIN-4-AMINE DERIVATIVES AS DEOXYCYTIDINE KINASE INHIBITORS FOR THE TREATMENT OF CANCER | Lexicon Pharmaceuticals, Inc. (US) | 2009-09-30 | — | — | EP | disclosed |
| WO-2008076779-A2 | 2-(PIPERIDIN-4-YL0XY)PYRIMIDIN-4-AMINE DERIVATIVES AS DEOXYCYTIDINE KINASE INHIBITORS FOR THE TREATMENT OF CANCER | LEXICON PHARMACEUTICALS, INC. (US) | 2008-06-26 | — | — | WO | disclosed |