Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27924178 | 0.77 | ABCB1 (0.37) | MAOBHTR2CHTR2AMAOAABCB1 | |
| SCHEMBL1328841 | 0.77 | POLB (0.43) | KDM1AKDM1BSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL1980720 | 0.77 | MAOB (0.41) | KDM1AKDM1BSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL18383187 | 0.77 | POLB (0.43) | KDM1AKDM1BSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL18383190 | 0.77 | POLB (0.43) | KDM1AKDM1BSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL15087649 | 0.77 | KDM1A (0.34) | KDM1AKDM1BSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL28513561 | 0.77 | HTR2C (0.37) | KDM1AKDM1BSLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL28513964 | 0.75 | HTR2C (0.39) | KDM1AKDM1BSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL14071736 | 0.74 | MAOB (0.45) | KDM1AKDM1BSLC6A2SLC6A3MAOB | |
| SCHEMBL1327438 | 0.73 | SLC6A2 (0.34) | KDM1AKDM1BSLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836486-A1 | DIAMINOPYRIMIDINES USEFUL AS INHIBITORS OF THE HUMAN RESPIRATORY SYNCYTIAL VIRUS (RSV) | AbbVie Inc. (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013123401-A1 | DIAMINOPYRIMIDINES USEFUL AS INHIBITORS OF THE HUMAN RESPIRATORY SYNCYTIAL VIRUS (RSV) | ABBVIE INC. (US) | 2013-08-22 | — | — | WO | disclosed |
| CN-101595110-A | Be used for immunosuppressant 7-substituted purin derivatives | PHARMACOPEIA INC (US) | 2009-12-02 | — | — | CN | disclosed |
| EP-2099800-A1 | 7-SUBSTITUTED PURINE DERIVATIVES FOR IMMUNOSUPPRESSION | Pharmacopeia, LLC (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008060301-A1 | 7-SUBSTITUTED PURINE DERIVATIVES FOR IMMUNOSUPPRESSION | PHARMACOPEIA , LLC (US) | 2008-05-22 | — | — | WO | disclosed |
| EP-1874772-A1 | PURINE AND IMIDAZOPYRIDINE DERIVATIVES FOR IMMUNOSUPPRESSION | PHARMACOPEIA, INC. (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006108103-A1 | PURINE AND IMIDAZOPYRIDINE DERIVATIVES FOR IMMUNOSUPPRESSION | PHARMACOPEIA, INC. (US) | 2006-10-12 | — | — | WO | disclosed |