Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4374243 | 0.78 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL3539241 | 0.76 | APEX1 (0.37) | HTR2AHTR2CHTR2B | |
| SCHEMBL4951664 | 0.76 | HTR2A (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL7666864 | 0.76 | HTR2B (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL11642650 | 0.75 | HTR2A (0.34) | HTR2AHTR2CHTR2B | |
| SCHEMBL1577842 | 0.73 | HTR2A (0.41) | HTR2AHTR2CHTR2B | |
| SCHEMBL7425481 | 0.73 | HTR2A (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL15653605 | 0.73 | HTR2A (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL6709305 | 0.69 | EDNRA (0.34) | — | |
| SCHEMBL7985531 | 0.69 | HTR2C (0.32) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687980-A1 | RADIOLABELED DARAPLADIB AND ANALOGS THEREOF AND THEIR USE AS IMAGING COMPOUNDS | Institut National de la Sante et de la Recherche Medicale (INSERM) (FR) | 2020-08-05 | — | — | EP | disclosed |
| WO-2019063634-A1 | RADIOLABELED DARAPLADIB AND ANALOGS THEREOF AND THEIR USE AS IMAGING COMPOUNDS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2019-04-04 | — | — | WO | disclosed |
| CN-103086936-A | Aryl compounds as PPAR ligands and their use | SEOUL NAT UNIV IND FOUNDATION (KR) | 2013-05-08 | — | — | CN | disclosed |
| CN-102863362-A | Aryl compounds as ppar ligands and their use | SEOUL NAT UNIV IND FOUNDATION (KR) | 2013-01-09 | — | — | CN | disclosed |
| CN-102584685-A | Aryl compounds as PPAR ligands and their use | SEOUL NAT UNIV IND FOUNDATION (KR) | 2012-07-18 | — | — | CN | disclosed |
| CN-101595089-A | Aryl compounds as PPAR ligands and uses thereof | SEOUL NAT UNIV IND FOUNDATION (KR) | 2009-12-02 | — | — | CN | disclosed |
| EP-2102155-A1 | ARYL COMPOUNDS AS PPAR LIGANDS AND THEIR USE | Seoul National University Industry Foundation (KR) | 2009-09-23 | — | — | EP | disclosed |
| CN-101346338-A | Dicarboxylic acid derivatives and their use | BAYER HEALTHCARE AG (DE) | 2009-01-14 | — | — | CN | disclosed |
| WO-2008066356-A1 | ARYL COMPOUNDS AS PPAR LIGANDS AND THEIR USE | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2008-06-05 | — | — | WO | disclosed |