Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL324970 | 0.95 | TSHR (0.64) | TSHRHPGDCES1CES2FAAH | |
| SCHEMBL325188 | 0.93 | TSHR (0.67) | TSHRCES1CES2FAAHALDH1A1 | |
| SCHEMBL9709313 | 0.93 | TSHR (0.67) | TSHRCES1CES2FAAHALDH1A1 | |
| SCHEMBL6126194 | 0.93 | TSHR (0.67) | TSHRCES1CES2FAAHALDH1A1 | |
| SCHEMBL4698282 | 0.89 | TSHR (0.50) | TSHRHPGDCES1CES2FAAH | |
| SCHEMBL352760 | 0.86 | TSHR (0.46) | TSHRHPGDCES1CES2FAAH | |
| SCHEMBL351663 | 0.82 | TSHR (0.53) | TSHRHPGDCES1CES2FAAH | |
| SCHEMBL16671847 | 0.81 | TSHR (0.40) | TSHRALDH1A1CYP3A4TDP1MAPT | |
| SCHEMBL9960430 | 0.81 | TSHR (0.40) | TSHRALDH1A1CYP3A4TDP1MAPT | |
| SCHEMBL352592 | 0.80 | TSHR (0.55) | TSHRCES1CES2FAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107759987-A | A kind of 3D printing toughness reinforcing PLA material | 黑龙江鑫达企业集团有限公司 | 2018-03-06 | — | — | CN | claimed |
| US-4690881-A | Liquid developer for electrophotography | RICOH CO., LTD. (JP) | 1987-09-01 | — | — | US | claimed |
| CN-110249019-B | Adhesive composition | 住友化学株式会社 | 2023-05-26 | — | — | CN | disclosed |
| CN-115594817-B | Acrylic acid modified polyurethane resin for pure water-based ink and preparation method thereof | 广州立诺新材料科技有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-110651017-B | Adhesive composition | 住友化学株式会社 | 2021-08-06 | — | — | CN | disclosed |
| CN-108368404-B | Adhesive composition | 住友化学株式会社 | 2020-10-30 | — | — | CN | disclosed |
| CN-110651017-A | Adhesive composition | 住友化学株式会社 | 2020-01-03 | — | — | CN | disclosed |
| CN-109749220-A | A kind of degradable shoes materials of novel pla-pcl and preparation method | 石狮市中纺学服装及配饰产业研究院 | 2019-05-14 | — | — | CN | disclosed |
| US-20190076687-A1 | Microcapsules, Method for Preparing Microcapsules, Fire-Extinguishing Agents, Materials, Coatings, and Articles Based Thereupon | LLC RUSINTECH (RU) | 2019-03-14 | — | — | US | disclosed |
| CN-107931530-A | A kind of sand mold riser runner and preparation method | 四川共享铸造有限公司 | 2018-04-20 | — | — | CN | disclosed |
| EP-3228366-A1 | MICROCAPSULES, METHOD FOR PRODUCING THEREOF AND FLAME RETARDANT AGENTS, MATERIALS, COATINGS AND PRODUCTS BASED THEREON | Limited Liability Company "Rusintech" (RU) | 2017-10-11 | — | — | EP | disclosed |
| US-20150322070-A1 | PIPERIDINE INHIBITORS OF JANUS KINASE 3 | AUSPEX PHARMACEUTICALS, INC. | 2015-11-12 | — | — | US | disclosed |
| EP-1651687-B1 | RANDOM ETHYLENE/ALKYL ACRYLATE COPOLYMERS, COMPOUNDS AND ELASTOMERIC COMPOSITIONS THEREOF WITH IMPROVED LOW TEMPERATURE PROPERTIES | DU PONT (US) | 2009-08-26 | — | — | EP | disclosed |
| US-7320854-B2 | Mixture of oxide particles, polymerizable compound,radiation sensitive decomposer and releasing agent | JSR CORPORATION (JP) | 2008-01-22 | — | — | US | disclosed |
| US-7153918-B2 | Random ethylene/alkyl acrylate copolymers, compounds and elastomeric compositions thereof with improved low temperature properties | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-12-26 | — | — | US | disclosed |
| US-20050020775-A1 | Random ethylene/alkyl acrylate copolymers, compounds and elastomeric compositions thereof with improved low temperature properties | DUPONT POLYMERS, INC. | 2005-01-27 | — | — | US | disclosed |
| EP-1494072-A2 | Radiation sensitive refractive index changing composition, pattern forming method and optical material | JSR Corporation (JP) | 2005-01-05 | — | — | EP | disclosed |
| US-20040265737-A1 | Radiation sensitive refractive index changing composition, pattern forming method and optical material | JSR CORPORATION (JP) | 2004-12-30 | — | — | US | disclosed |
| WO-1990003411-A1 | METHOD OF PREPARING REINFORCED RUBBER AND REINFORCED RUBBER PRODUCTS | INSTITUTET POLYMERUTVECKLING AB (SE) | 1990-04-05 | — | — | WO | disclosed |
| US-4690881-A | Liquid developer for electrophotography | RICOH CO., LTD. (JP) | 1987-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322070-A1 | PIPERIDINE INHIBITORS OF JANUS KINASE 3 | JAK2, JAK3, PAK3 | TSHR 3548/4885HPGD 1697/4885CES1 2452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.