Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.67 |
| ▸ | FAAH | O00519 | 3/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | PPARD | Q03181 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6126194 | 1.00 | TSHR (0.67) | TSHRFAAHDGKACES2CES1 | |
| SCHEMBL325188 | 1.00 | TSHR (0.67) | TSHRFAAHDGKACES2CES1 | |
| SCHEMBL324970 | 0.98 | TSHR (0.64) | TSHRFAAHDGKACES2CES1 | |
| SCHEMBL3834150 | 0.93 | TSHR (0.56) | TSHRFAAHDGKACES2CES1 | |
| SCHEMBL351339 | 0.87 | TSHR (0.55) | TSHRFAAHDGKACES2CES1 | |
| SCHEMBL352592 | 0.87 | TSHR (0.55) | TSHRFAAHDGKACES2CES1 | |
| SCHEMBL352230 | 0.87 | TSHR (0.55) | TSHRFAAHDGKACES2CES1 | |
| SCHEMBL350681 | 0.87 | TSHR (0.55) | TSHRFAAHDGKACES2CES1 | |
| SCHEMBL352699 | 0.87 | TSHR (0.55) | TSHRFAAHDGKACES2CES1 | |
| SCHEMBL353116 | 0.87 | TSHR (0.55) | TSHRFAAHDGKACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171267-A | Surface-modified self-passivating intraocular lenses | THE BOARD OF REGENTS OF THE UNIVERSITY OF WASHINGTON (US) | 1992-12-15 | — | — | US | disclosed |
| WO-1992016168-A1 | SURFACE-MODIFIED SELF-PASSIVATING INTRAOCULAR LENSES | THE BOARD OF REGENTS OF THE UNIVERSITY OF WASHINGTON (US) | 1992-10-01 | — | — | WO | disclosed |