Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.74 |
| ▸ | PAM | P19021 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | CES1 | P23141 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PRKCA | P17252 | 1/20 | 0.53 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.53 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.53 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10911616 | 1.00 | DGKA (0.74) | DGKAPAMTSHRMAPTLMNA | |
| SCHEMBL11220576 | 0.97 | DGKA (0.78) | DGKAPAMTSHRMAPTLMNA | |
| SCHEMBL3836403 | 0.97 | DGKA (0.78) | DGKAPAMTSHRMAPTLMNA | |
| SCHEMBL2502982 | 0.97 | DGKA (0.78) | DGKAPAMTSHRMAPTLMNA | |
| SCHEMBL11229514 | 0.97 | DGKA (0.78) | DGKAPAMTSHRMAPTLMNA | |
| SCHEMBL15891850 | 0.97 | DGKA (0.78) | DGKAPAMTSHRMAPTLMNA | |
| SCHEMBL3834771 | 0.97 | DGKA (0.78) | DGKAPAMTSHRMAPTLMNA | |
| SCHEMBL11226064 | 0.97 | DGKA (0.78) | DGKAPAMTSHRMAPTLMNA | |
| SCHEMBL11226211 | 0.97 | DGKA (0.78) | DGKAPAMTSHRMAPTLMNA | |
| SCHEMBL3835588 | 0.97 | DGKA (0.78) | DGKAPAMTSHRMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448508-B1 | DOUBLE ESTERS | DRUG DISCOVERY LAB AS (NO) | 2009-09-23 | — | — | EP | disclosed |
| EP-1448508-A1 | DOUBLE ESTERS | Photocure ASA (NO) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003045893-A1 | DOUBLE ESTERS | PHOTOCURE ASA (NO) | 2003-06-05 | — | — | WO | disclosed |