SCHEMBL3834366

SCHEMBL3834366

C=CCC(C(=O)OCC)c1ccc(OC)c(OC)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.50
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
ALDH1A1 P00352 6/20 0.44
HTT P42858 2/20 0.44
PKM P14618 1/20 0.44
LMNA P02545 3/20 0.43
CCR3 P51677 1/20 0.42
MAPT P10636 2/20 0.42
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
KMT2A Q03164 1/20 0.42
ACHE P22303 1/20 0.42
CYP2C19 P33261 1/20 0.41
PPARG P37231 2/20 0.41
PPARD Q03181 2/20 0.41
PPARA Q07869 2/20 0.41
LDHA P00338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3828450 0.88 CA12 (0.47) HIF1ACA12CA1CA2CA9
SCHEMBL11582477 0.86 CA12 (0.52) HIF1ACA12CA1CA2CA9
SCHEMBL3829775 0.85 CYP2C19 (0.55) HIF1ACA12CA1CA2CA9
SCHEMBL18255541 0.85 HIF1A (0.53) HIF1AALDH1A1HTTLMNACCR3
SCHEMBL3835048 0.83 PPARG (0.53) HIF1ACA12CA1CA2CA9
SCHEMBL18252783 0.82 HIF1A (0.51) HIF1ACA1CA2ALDH1A1HTT
SCHEMBL5743088 0.82 CA12 (0.52) HIF1ACA12CA1CA2CA9
Hydrochloric Acid SCHEMBL5743084 0.81 CA12 (0.51) HIF1ACA12CA1CA2CA9
SCHEMBL11209507 0.80 APP (0.48) HIF1AALDH1A1LMNACCR3ACHE
SCHEMBL9383072 0.80 CA12 (0.47) HIF1ACA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2102168-A1 ACYLAMINOPYRAZOLES FOR TREATING CARDIOVASCULAR DISEASES Bayer Schering Pharma Aktiengesellschaft (DE) 2009-09-23 EP disclosed
EP-2079708-A2 ACYL AMINOIMIDAZOLES AND ACYL AMINOTHIAZOLES Bayer HealthCare AG (DE) 2009-07-22 EP disclosed
WO-2008046527-A1 ACYLAMINOPYRAZOLES FOR TREATING CARDIOVASCULAR DISEASES BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-04-24 WO disclosed
WO-2008046527-A1 ACYLAMINOPYRAZOLES FOR TREATING CARDIOVASCULAR DISEASES BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-04-24 WO disclosed
WO-2008043533-A2 ACYL AMINOIMIDAZOLES AND ACYL AMINOTHIAZOLES BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-04-17 WO disclosed
WO-2008043533-A2 ACYL AMINOIMIDAZOLES AND ACYL AMINOTHIAZOLES BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-04-17 WO disclosed
WO-2007082666-A1 ACYLAMINOIMIDAZOLES BAYER HEALTHCARE AG (DE) 2007-07-26 WO disclosed
WO-2007082666-A1 ACYLAMINOIMIDAZOLES BAYER HEALTHCARE AG (DE) 2007-07-26 WO disclosed