Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306255 | 0.92 | P2RX3 (0.46) | P2RX3EPHX2ADAMTS5ADAMTS4ALDH1A1 | |
| SCHEMBL1306257 | 0.92 | P2RX3 (0.46) | P2RX3EPHX2ADAMTS5ADAMTS4ALDH1A1 | |
| SCHEMBL1305517 | 0.86 | P2RX3 (0.46) | P2RX3EPHX2ADAMTS5ADAMTS4MAPT | |
| SCHEMBL1305514 | 0.86 | P2RX3 (0.46) | P2RX3EPHX2ADAMTS5ADAMTS4MAPT | |
| SCHEMBL1305917 | 0.86 | P2RX3 (0.45) | P2RX3ADAMTS5ADAMTS4ALDH1A1 | |
| SCHEMBL1305915 | 0.86 | P2RX3 (0.45) | P2RX3ADAMTS5ADAMTS4ALDH1A1 | |
| SCHEMBL1306690 | 0.85 | P2RX3 (0.47) | P2RX3ADAMTS5ADAMTS4MAPTALDH1A1 | |
| SCHEMBL1306688 | 0.85 | P2RX3 (0.47) | P2RX3ADAMTS5ADAMTS4MAPTALDH1A1 | |
| SCHEMBL3833477 | 0.85 | P2RX3 (0.47) | P2RX3ADAMTS5ADAMTS4ALDH1A1PREP | |
| SCHEMBL1307169 | 0.85 | P2RX3 (0.55) | P2RX3ADAMTS5ADAMTS4ALDH1A1PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2913322-A2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | Korea Research Institute Of Chemical Technology (KR) | 2015-09-02 | — | — | EP | disclosed |
| EP-2089354-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Korea Research Institute Of Chemical Technology (KR) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008054154-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-08 | — | — | WO | disclosed |