⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8149855 | 0.81 | — | — | |
| SCHEMBL14366518 | 0.78 | LMNA (0.42) | — | |
| SCHEMBL58897 | 0.78 | LMNA (0.42) | — | |
| SCHEMBL10759511 | 0.78 | — | — | |
| SCHEMBL5586687 | 0.74 | — | — | |
| SCHEMBL13997319 | 0.72 | LMNA (0.36) | — | |
| SCHEMBL17574431 | 0.72 | LMNA (0.36) | — | |
| SCHEMBL5936391 | 0.72 | LMNA (0.36) | — | |
| SCHEMBL12572606 | 0.72 | LMNA (0.36) | — | |
| SCHEMBL14116702 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000003699-A2 | DRUGS CONTAINING PHOSPHORIC ACID DERIVATIVES AS ACTIVE INGREDIENT AND THEIR USE | HASSAN JOMAA (DE) | 2000-01-27 | — | — | WO | claimed |
| EP-1549658-B1 | GLUCOSE-BASED COMPOUNDS WITH AFFINITY TO P-SELECTIN | ASTELLAS PHARMA EUROP B V (NL) | 2009-09-30 | — | — | EP | disclosed |
| US-7304039-B2 | Glucose-based compounds with affinity to P-selectin | ASTELLAS PHARMA EUROPE B.V. (NL) | 2007-12-04 | — | — | US | disclosed |
| US-20050261207-A1 | Glucose-based compounds with affinity to p-selectin | YAMANOUCHI EUROPE B.V. (NL) | 2005-11-24 | — | — | US | disclosed |
| EP-1549658-A1 | GLUCOSE-BASED COMPOUNDS WITH AFFINITY TO P-SELECTIN | YAMANOUCHI EUROPE B.V. (NL) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004033473-A1 | GLUCOSE-BASED COMPOUNDS WITH AFFINITY TO P-SELECTIN | YAMANOUCHI EUROPE B.V. (NL) | 2004-04-22 | — | — | WO | disclosed |