Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 4/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28081733 | 0.82 | SCN4A (0.51) | ELANEKMT2AHPGDSCN4ACYP3A4 | |
| SCHEMBL29256404 | 0.81 | ELANE (0.42) | ELANEKMT2ALMNAHPGDHTT | |
| SCHEMBL2016284 | 0.78 | DPP4 (0.49) | ELANEKMT2AHTTSMN1; SMN2SCN4A | |
| SCHEMBL4447785 | 0.78 | DPP4 (0.49) | ELANEKMT2AHTTSMN1; SMN2SCN4A | |
| SCHEMBL23356900 | 0.78 | DPP4 (0.49) | ELANEKMT2AHTTSMN1; SMN2SCN4A | |
| SCHEMBL7978485 | 0.78 | SMN1; SMN2 (0.44) | ELANEKMT2AHPGDHTTSMN1; SMN2 | |
| SCHEMBL4881023 | 0.78 | CHRNB4 (0.39) | ELANESCN4ACYP3A4CYP2D6CYP1A2 | |
| SCHEMBL3499943 | 0.78 | SMN1; SMN2 (0.44) | ELANEKMT2AHPGDHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10521985 | 0.77 | DPP4 (0.50) | ELANEKMT2AHPGDHTTSMN1; SMN2 | |
| SCHEMBL29157407 | 0.77 | SCN4A (0.35) | ELANEHPGDSCN4ACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125870-A1 | INHIBITORS OF HEPATITIS C NS3 PROTEASE | Boehringer Ingelheim International GmbH (DE) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008098368-A1 | INHIBITORS OF HEPATITIS C NS3 PROTEASE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-21 | — | — | WO | disclosed |