Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978485 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTCYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL1653893 | 0.89 | GPR35 (0.39) | SMN1; SMN2MAPTCYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL27692446 | 0.84 | MAPT (0.42) | SMN1; SMN2MAPTCYP1A2ALDH1A1TDP1 | |
| SCHEMBL7982064 | 0.84 | KDM4E (0.39) | SMN1; SMN2MAPTALDH1A1TDP1RAB9A | |
| SCHEMBL7134426 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTCYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL9027345 | 0.79 | RAB9A (0.54) | SMN1; SMN2MAPTCYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL11336164 | 0.79 | MAPT (0.41) | SMN1; SMN2MAPTCYP1A2ALDH1A1L3MBTL1 | |
| SCHEMBL12869701 | 0.79 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1KMT2AHTTELANE | |
| SCHEMBL3835050 | 0.78 | ELANE (0.43) | SMN1; SMN2CYP1A2CYP2C9L3MBTL1RAB9A | |
| SCHEMBL28081733 | 0.78 | SCN4A (0.51) | CYP1A2CYP2C9KMT2AELANEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8541005-B2 | Cysteine-tagged streptococcal protein G variant | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2013-09-24 | — | — | US | claimed |
| US-20100173430-A1 | CYSTEINE-TAGGED STAPHYLOCOCCAL PROTEIN G VARIANT | KOREAN RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2010-07-08 | — | — | US | claimed |
| EP-2046816-A1 | CYSTEINE-TAGGED STAPHYLOCOCCAL PROTEIN G VARIANT | Korea Research Institute of Bioscience and Biotechnology (KR) | 2009-04-15 | — | — | EP | claimed |
| WO-2008016221-A1 | CYSTEINE-TAGGED STAPHYLOCOCCAL PROTEIN G VARIANT | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2008-02-07 | — | — | WO | claimed |
| US-8541005-B2 | Cysteine-tagged streptococcal protein G variant | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2013-09-24 | — | — | US | disclosed |
| US-20100203653-A1 | Protein G-Oligonucleotide Conjugate | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2010-08-12 | — | — | US | disclosed |
| US-20100173430-A1 | CYSTEINE-TAGGED STAPHYLOCOCCAL PROTEIN G VARIANT | KOREAN RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2010-07-08 | — | — | US | disclosed |
| EP-2046816-A1 | CYSTEINE-TAGGED STAPHYLOCOCCAL PROTEIN G VARIANT | Korea Research Institute of Bioscience and Biotechnology (KR) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008016221-A1 | CYSTEINE-TAGGED STAPHYLOCOCCAL PROTEIN G VARIANT | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2008-02-07 | — | — | WO | disclosed |
| US-6225306-B1 | PYRROLO(1,2A)QUINOXALINES | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-01 | — | — | US | disclosed |
| EP-0987266-A1 | BIPHENYL DERIVATIVES AND MEDICINAL COMPOSITIONS | Wakamoto Pharmaceutical Co., Ltd. (JP) | 2000-03-22 | — | — | EP | disclosed |