Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UPP1 | Q16831 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | DPYD | Q12882 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584505 | 0.74 | UPP1 (0.59) | UPP1KDM4ERECQLTDP1ALDH1A1 | |
| SCHEMBL6516876 | 0.72 | UPP1 (0.57) | UPP1KDM4EALDH1A1MCL1DPYD | |
| SCHEMBL3812728 | 0.69 | UPP1 (0.53) | UPP1KDM4EALDH1A1MCL1DPYD | |
| SCHEMBL24218091 | 0.67 | GRIN2D (0.41) | UPP1KDM4ERECQLTDP1ALDH1A1 | |
| SCHEMBL30903890 | 0.66 | UPP1 (0.49) | UPP1KDM4EALDH1A1TRPV4MCL1 | |
| SCHEMBL31575258 | 0.66 | UPP1 (0.49) | UPP1KDM4EALDH1A1MCL1DPYD | |
| SCHEMBL194923 | 0.65 | — | — | |
| SCHEMBL1006471 | 0.64 | CA12 (0.55) | UPP1KDM4EALDH1A1MCL1CRHBP | |
| Hydrochloric Acid SCHEMBL30903877 | 0.63 | CA12 (0.53) | UPP1KDM4EALDH1A1MCL1CRHBP | |
| SCHEMBL2741330 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592455-B2 | Bicyclic heteroaromatic compounds as kinase inhibitors | UCB PHARMA S.A. (BE) | 2009-09-22 | — | — | US | disclosed |
| US-20060025428-A1 | Bicyclic heteroaromatic compounds as kinase inhibitors | UCB PHARMA S.A. (BE) | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025428-A1 | Bicyclic heteroaromatic compounds as kinase inhibitors | MAP2K2, MAP2K7, MAP2K6 | UPP1 1303/4885KDM4E 2548/4885RECQL 2948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.