Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 17/20 | 0.78 |
| ▸ | RARB | P10826 | 16/20 | 0.78 |
| ▸ | RARA | P10276 | 14/20 | 0.78 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382466 | 0.88 | RARG (1.00) | RARGRARBRARA | |
| SCHEMBL382215 | 0.85 | RARG (0.77) | RARGRARBRARA | |
| SCHEMBL382587 | 0.84 | RARA (0.80) | RARGRARBRARA | |
| SCHEMBL382960 | 0.82 | RARB (0.56) | RARGRARBRARAGAA | |
| SCHEMBL382732 | 0.82 | RARG (0.65) | RARGRARBRARALMNAGAA | |
| SCHEMBL383570 | 0.80 | RARG (0.62) | RARGRARBRARA | |
| SCHEMBL381528 | 0.80 | RARG (0.79) | RARGRARBRARA | |
| SCHEMBL382828 | 0.80 | RARG (0.61) | RARGRARBRARALMNA | |
| SCHEMBL383242 | 0.79 | RARG (0.79) | RARGRARBRARA | |
| SCHEMBL382183 | 0.78 | RARG (0.80) | RARGRARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831149-B1 | NOVEL LIGANDS THAT MODULATE RAR RECEPTORS AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2012-01-25 | — | — | EP | claimed |