Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | GNRHR | P30968 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3233628 | 0.90 | AVPR1A (0.43) | AVPR1AALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL3230306 | 0.83 | HTT (0.43) | AVPR1AALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL3230218 | 0.83 | ALDH1A1 (0.40) | AVPR1AALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL3236849 | 0.82 | AVPR1A (0.45) | AVPR1AALDH1A1MAPTRECQLLMNA | |
| SCHEMBL3235051 | 0.82 | AVPR1A (0.43) | AVPR1AALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL3235527 | 0.82 | GNRHR (0.39) | AVPR1AALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL3226270 | 0.82 | GNRHR (0.39) | AVPR1AALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL3234537 | 0.82 | AVPR1A (0.45) | AVPR1AALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL3228428 | 0.82 | AVPR1A (0.43) | AVPR1AALDH1A1HPGDMAPTRECQL | |
| SCHEMBL3234028 | 0.82 | GNRHR (0.39) | AVPR1AALDH1A1MAPTRECQLGNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097374-A2 | 5-ALKYLOXY-INDOLIN-2-ONE DERIVATIVES, PREPARATION THEREOF AND APPLICATION THEREOF IN THERAPY AS SELECTIVE LIGANDS OF V2 VASOPRESSIN RECEPTORS | Sanofi-Aventis (FR) | 2009-09-09 | — | — | EP | claimed |
| WO-2008087278-A2 | 5-ALKYLOXY-INDOLIN-2-ONE DERIVATIVES, PREPARATION THEREOF AND APPLICATION THEREOF IN THERAPY AS SELECTIVE LIGANDS OF V2 VASOPRESSIN RECEPTORS | SANOFI-AVENTIS (FR) | 2008-07-24 | — | — | WO | claimed |