Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 16/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3836423 | 0.82 | GRM5 (0.58) | GRM5NPC1RAB9A | |
| SCHEMBL3836422 | 0.82 | GRM5 (0.58) | GRM5NPC1RAB9A | |
| SCHEMBL3837282 | 0.82 | GRM5 (0.58) | GRM5NPC1RAB9A | |
| SCHEMBL3835764 | 0.80 | GRM5 (0.46) | GRM5NPC1RAB9AEPHX2 | |
| SCHEMBL3860245 | 0.79 | GRM5 (0.52) | GRM5 | |
| SCHEMBL3836458 | 0.79 | GRM5 (0.52) | GRM5 | |
| SCHEMBL3836455 | 0.79 | GRM5 (0.52) | GRM5 | |
| SCHEMBL3841794 | 0.79 | GRM5 (0.46) | GRM5RAB9AEPHX2 | |
| SCHEMBL3841449 | 0.79 | GRM5 (0.46) | GRM5RAB9AEPHX2 | |
| SCHEMBL3840495 | 0.79 | GRM5 (0.43) | GRM5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877367-B1 | ACETYLENE DERIVATIVES | NOVARTIS AG (CH) | 2009-10-14 | — | — | EP | claimed |