SCHEMBL383674

CCCC[Si](C)(C)O[C@@H]1[C@H](O)[C@@H](C(OC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)C(C)=O)O[C@H]1n1ccc(N)nc1=O

nearest known ligand 0.38

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	ST6GAL1	P15907	7/20	0.38

▸	L3MBTL1	Q9Y468	1/20	0.37

▸	NT5E	P21589	1/20	0.35

▸	LMNA	P02545	1/20	0.35

▸	THRB	P10828	1/20	0.35

▸	MTOR	P42345	1/20	0.35

▸	MDM2	Q00987	1/20	0.35

▸	NCOA1	Q15788	1/20	0.35

▸	NCOA3	Q9Y6Q9	1/20	0.35

▸	TYMP	P19971	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL381896	0.88	ST6GAL1 (0.38)	ST6GAL1NT5ELMNATHRBMTOR
SCHEMBL384046	0.86	ST6GAL1 (0.36)	ST6GAL1L3MBTL1NT5ELMNATHRB
SCHEMBL1318619	0.86	NT5E (0.45)	ST6GAL1L3MBTL1NT5ELMNATHRB
SCHEMBL1317526	0.86	NT5E (0.45)	ST6GAL1L3MBTL1NT5ELMNATHRB
SCHEMBL17599881	0.84	ST6GAL1 (0.40)	ST6GAL1NT5ELMNATHRBMTOR
SCHEMBL1319027	0.83	ST6GAL1 (0.37)	ST6GAL1NT5ELMNATHRBMTOR
SCHEMBL2216432	0.82	ST6GAL1 (0.36)	ST6GAL1NT5ELMNATHRBMTOR
SCHEMBL2107080	0.82	ST6GAL1 (0.36)	ST6GAL1NT5ELMNATHRBMTOR
SCHEMBL4760169	0.82	ST6GAL1 (0.36)	ST6GAL1NT5ELMNATHRBMTOR
SCHEMBL15993819	0.81	ST6GAL1 (0.38)	ST6GAL1NT5ELMNATHRBMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2408306-A1	SUBSTITUTED NUCLEOSIDE AND NUCLEOTIDE ANALOGS	Alios Biopharma, Inc. (US)	2012-01-25	—	—	EP	disclosed