Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST6GAL1 | P15907 | 7/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1317526 | 0.89 | NT5E (0.45) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL1318619 | 0.89 | NT5E (0.45) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL383674 | 0.88 | ST6GAL1 (0.38) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL17599881 | 0.87 | ST6GAL1 (0.40) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL1319027 | 0.86 | ST6GAL1 (0.37) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL4458009 | 0.84 | ST6GAL1 (0.42) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL2216432 | 0.84 | ST6GAL1 (0.36) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL2814330 | 0.84 | ST6GAL1 (0.35) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL4760169 | 0.83 | ST6GAL1 (0.36) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL2107080 | 0.83 | ST6GAL1 (0.36) | ST6GAL1NT5ELMNATHRBMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2623104-A1 | Substituted nucleoside and nucleotide analogs | Alios Biopharma, Inc. (US) | 2013-08-07 | — | — | EP | disclosed |
| EP-2408306-A1 | SUBSTITUTED NUCLEOSIDE AND NUCLEOTIDE ANALOGS | Alios Biopharma, Inc. (US) | 2012-01-25 | — | — | EP | disclosed |
| US-20100249068-A1 | SUBSTITUTED NUCLEOSIDE AND NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. (US) | 2010-09-30 | — | — | US | disclosed |
| WO-2010108140-A1 | SUBSTITUTED NUCLEOSIDE AND NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. (US) | 2010-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249068-A1 | SUBSTITUTED NUCLEOSIDE AND NUCLEOTIDE ANALOGS | PNP, TYMP, NTPCR | ST6GAL1 1533/4885NT5E 19/4885LMNA 1477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.