Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3836769 | 1.00 | MAPT (0.33) | MAPTALDH1A1 | |
| SCHEMBL4098274 | 0.87 | ALDH1A1 (0.35) | MAPTALDH1A1 | |
| SCHEMBL4098275 | 0.87 | ALDH1A1 (0.35) | MAPTALDH1A1 | |
| SCHEMBL10195624 | 0.76 | ALDH1A1 (0.33) | MAPTALDH1A1 | |
| SCHEMBL4111714 | 0.76 | CYP2C9 (0.51) | MAPTALDH1A1 | |
| SCHEMBL4111710 | 0.76 | CYP2C9 (0.51) | MAPTALDH1A1 | |
| SCHEMBL4100792 | 0.74 | ALDH1A1 (0.31) | MAPTALDH1A1 | |
| SCHEMBL4100796 | 0.74 | ALDH1A1 (0.31) | MAPTALDH1A1 | |
| SCHEMBL12236287 | 0.67 | KCNH2 (0.40) | — | |
| SCHEMBL12873334 | 0.63 | KCNH2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220091-A2 | REVERSE TRANSCRIPTASE INHIBITORS | Ardea Biosciences, Inc. (US) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009079412-A2 | REVERSE TRANSCRIPTASE INHIBITORS | ARDEA BIOSCIENCES INC. (US) | 2009-06-25 | — | — | WO | disclosed |