Sugi Predict

Sugi Predict / Compounds / SCHEMBL3836844

SCHEMBL3836844

SCHEMBL3836844

Nc1c(Cl)ccc(Br)c1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGER4 P35408 1/20 0.43
▸ CDC7 O00311 1/20 0.38
▸ EEF2K O00418 1/20 0.38
▸ PLK4 O00444 1/20 0.38
▸ AURKA O14965 1/20 0.38
▸ DAPK3 O43293 1/20 0.38
▸ ROCK2 O75116 1/20 0.38
▸ RPS6KA5 O75582 1/20 0.38
▸ PRKD3 O94806 1/20 0.38
▸ MAP4K4 O95819 1/20 0.38
▸ INSR P06213 1/20 0.38
▸ CDK1 P06493 1/20 0.38
▸ CSF1R P07333 1/20 0.38
▸ IGF1R P08069 1/20 0.38
▸ ROS1 P08922 1/20 0.38
▸ PIM1 P11309 1/20 0.38
▸ PHKG2 P15735 1/20 0.38
▸ PRKACA P17612 1/20 0.38
▸ FLT1 P17948 1/20 0.38
▸ FGFR3 P22607 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20636586 0.81 CA1 (0.40) PTGER4CDC7EEF2KPLK4AURKA
SCHEMBL239457 0.79 PTGER4 (0.43) PTGER4CDC7EEF2KPLK4AURKA
SCHEMBL31387674 0.79 PTGER4 (0.43) PTGER4CDC7EEF2KPLK4AURKA
SCHEMBL9365624 0.77 TSHR (0.41) TSHRCYP3A4CA1CA2CA9
SCHEMBL31167425 0.77 TSHR (0.41) TSHRCYP3A4CA1CA2CA9
SCHEMBL23229374 0.75 PTGER4 (0.41) PTGER4CDC7EEF2KPLK4AURKA
SCHEMBL20595059 0.75 PTGER4 (0.41) PTGER4CA1CA2CA9HTR2A
SCHEMBL20873035 0.75 CDC7 (0.40) CDC7EEF2KPLK4AURKADAPK3
SCHEMBL23944606 0.75 CDC7 (0.36) PTGER4CDC7EEF2KPLK4AURKA
SCHEMBL1224150 0.75 CDC7 (0.36) PTGER4CDC7EEF2KPLK4AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2060566-B1 Poly-substituted aryls DOW AGROSCIENCES LLC (US) 2016-06-08 — — EP claimed
EP-2060566-A1 Poly-substituted aryls Dow AgroSciences LLC (US) 2009-05-20 — — EP claimed
EP-1973881-A2 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES Dow Agrosciences LLC (US) 2008-10-01 — — EP claimed
US-20080051596-A1 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides DOW AGROSCIENCES LLC (US) 2008-02-28 — — US claimed
US-20070179060-A1 6-(Poly-substituted aryl)-4-aminopicolinates and their use as herbicides CORTEVA AGRISCIENCE LLC 2007-08-02 — — US claimed
WO-2007082098-A2 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2007-07-19 — — WO claimed
CN-117326949-A Preparation method of 2, 4-dichloro-3-nitrobenzoic acid 清源创新实验室 2024-01-02 — — CN disclosed
CN-109704972-A The preparation method of one kind 2,3,4- trifluoronitrobenzene 张天冬 2019-05-03 — — CN disclosed
CN-102731381-B The polysubstituted aryl of 6-()-4-aminopyridine formic acid esters and the purposes as herbicide thereof 美国陶氏益农公司 2016-08-17 — — CN disclosed
EP-2060566-B1 Poly-substituted aryls DOW AGROSCIENCES LLC (US) 2016-06-08 — — EP disclosed
EP-1973881-B1 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2009-10-28 — — EP disclosed
EP-2060566-A1 Poly-substituted aryls Dow AgroSciences LLC (US) 2009-05-20 — — EP disclosed
US-7498468-B2 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides DOW AGROSCIENCES LLC (US) 2009-03-03 — — US disclosed
US-20080051596-A1 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides DOW AGROSCIENCES LLC (US) 2008-02-28 — — US disclosed
US-20080045734-A1 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides DOW AGROSCIENCES LLC (US) 2008-02-21 — — US disclosed
US-7314849-B2 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides DOW AGROSCIENCES LLC (US) 2008-01-01 — — US disclosed
US-20070179060-A1 6-(Poly-substituted aryl)-4-aminopicolinates and their use as herbicides CORTEVA AGRISCIENCE LLC 2007-08-02 — — US disclosed
WO-2007082098-A2 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2007-07-19 — — WO disclosed
EP-0421216-B1 Process for the preparation of 2,4, resp. 2,6 dihalo-aniline BAYER AG (DE) 1993-10-27 — — EP disclosed
US-5145958-A Process for the preparation of 2,4- or 2,6-dihalogeno-aniline BAYER AKTIENGESELLSCHAFT (DE) 1992-09-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080045734-A1 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides AAAS, DDT, AADAC PTGER4 4102/4885CDC7 3044/4885EEF2K 2770/4885
US-20070179060-A1 6-(Poly-substituted aryl)-4-aminopicolinates and their use as herbicides AAAS, DDT, AADAC PTGER4 4102/4885CDC7 3044/4885EEF2K 2770/4885
US-20080051596-A1 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides AAAS, DDT, AADAC PTGER4 4102/4885CDC7 3044/4885EEF2K 2770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.