SCHEMBL23944606

SCHEMBL23944606

Nc1c(Cl)ccc(Br)c1I

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC7 O00311 1/20 0.36
EEF2K O00418 1/20 0.36
PLK4 O00444 1/20 0.36
AURKA O14965 1/20 0.36
DAPK3 O43293 1/20 0.36
ROCK2 O75116 1/20 0.36
RPS6KA5 O75582 1/20 0.36
PRKD3 O94806 1/20 0.36
MAP4K4 O95819 1/20 0.36
INSR P06213 1/20 0.36
CDK1 P06493 1/20 0.36
CSF1R P07333 1/20 0.36
IGF1R P08069 1/20 0.36
ROS1 P08922 1/20 0.36
PIM1 P11309 1/20 0.36
PHKG2 P15735 1/20 0.36
PRKACA P17612 1/20 0.36
FLT1 P17948 1/20 0.36
FGFR3 P22607 1/20 0.36
RPS6KB1 P23443 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20636586 0.77 CA1 (0.40) CDC7EEF2KPLK4AURKADAPK3
SCHEMBL31505731 0.75 AXL (0.34) CA1CA2CA9ALDH1A1
SCHEMBL3836844 0.75 PTGER4 (0.43) CDC7EEF2KPLK4AURKADAPK3
SCHEMBL15494763 0.75 AXL (0.34) CA1CA2CA9ALDH1A1
SCHEMBL1903071 0.71 ALDH1A1 (0.38) CDC7EEF2KPLK4AURKADAPK3
SCHEMBL1224150 0.71 CDC7 (0.36) CDC7EEF2KPLK4AURKADAPK3
SCHEMBL31251851 0.71 NOTUM (0.30)
SCHEMBL20873035 0.71 CDC7 (0.40) CDC7EEF2KPLK4AURKADAPK3
SCHEMBL23403883 0.71 NOTUM (0.30)
SCHEMBL2359630 0.69 TSHR (0.47) TSHRCA1CA2CA9CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021210910-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-10-21 WO disclosed