Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246054 | 0.86 | ALDH1A1 (0.55) | ALDH1A1TSHRTAAR1AOC3HRH3 | |
| Trimethylammonium SCHEMBL210363 | 0.85 | ALDH1A1 (0.43) | ALDH1A1TSHRTAAR1AOC3SLC6A2 | |
| SCHEMBL8492024 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRTAAR1AOC3SLC6A2 | |
| SCHEMBL15850 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHR | |
| SCHEMBL29395089 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHR | |
| SCHEMBL187720 | 0.79 | SLC6A4 (0.44) | ALDH1A1TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11805829 | 0.79 | ALDH1A1 (0.45) | ALDH1A1TSHR | |
| SCHEMBL21835033 | 0.79 | MEN1 (0.39) | ALDH1A1TSHRTAAR1HRH3SLC6A2 | |
| Phosphine SCHEMBL9146532 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL11329466 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1151090-B1 | MULTIPLE ENZYME ASSAYS | APPLERA CORP (US) | 2009-09-02 | — | — | EP | claimed |
| EP-0874913-B1 | MULTIPLE REPORTER GENE ASSAY | APPLERA CORP (US) | 2008-06-25 | — | — | EP | claimed |
| EP-1151090-A4 | MULTIPLE ENZYME ASSAYS | APPLERA CORP (US) | 2007-05-02 | — | — | EP | claimed |
| US-6602657-B1 | Measuring the light signal produced by degradation of the substrates by the reporter enzymes; sequentially performed on the same aliquot of sample; used for detecting transcriptional activity in a cell | TROPIX, INC. | 2003-08-05 | — | — | US | claimed |
| EP-0874913-A4 | MULTIPLE REPORTER GENE ASSAY | TROPIX INC (US) | 2003-07-30 | — | — | EP | claimed |
| JP-2003520017-A | — | — | 2003-07-02 | — | — | JP | claimed |
| US-6586196-B1 | Multiple enzyme assays | TROPIX, INC. | 2003-07-01 | — | — | US | claimed |
| EP-1151090-A1 | MULTIPLE ENZYME ASSAYS | TROPIX, INC. (US) | 2001-11-07 | — | — | EP | claimed |
| WO-2000036098-A1 | MULTIPLE ENZYME ASSAYS | TROPIX, INC. (US) | 2000-06-22 | — | — | WO | claimed |
| EP-0874913-A1 | MULTIPLE REPORTER GENE ASSAY | TROPIX, INC. (US) | 1998-11-04 | — | — | EP | claimed |
| WO-1997024460-A1 | MULTIPLE REPORTER GENE ASSAY | TROPIX, INC. (US) | 1997-07-10 | — | — | WO | claimed |
| EP-1151090-B1 | MULTIPLE ENZYME ASSAYS | APPLERA CORP (US) | 2009-09-02 | — | — | EP | disclosed |
| EP-0874913-B1 | MULTIPLE REPORTER GENE ASSAY | APPLERA CORP (US) | 2008-06-25 | — | — | EP | disclosed |
| EP-1151090-A4 | MULTIPLE ENZYME ASSAYS | APPLERA CORP (US) | 2007-05-02 | — | — | EP | disclosed |
| US-6602658-B1 | Initiating two luciferase-mediated luminescence reactions; quantifying and quenching luminescence; adding an accelerator solution to inactivate first reaction | TROPIX, INC. | 2003-08-05 | — | — | US | disclosed |
| US-6586196-B1 | Multiple enzyme assays | TROPIX, INC. | 2003-07-01 | — | — | US | disclosed |
| EP-1151090-A1 | MULTIPLE ENZYME ASSAYS | TROPIX, INC. (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000036098-A1 | MULTIPLE ENZYME ASSAYS | TROPIX, INC. (US) | 2000-06-22 | — | — | WO | disclosed |
| EP-0874913-A1 | MULTIPLE REPORTER GENE ASSAY | TROPIX, INC. (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997024460-A1 | MULTIPLE REPORTER GENE ASSAY | TROPIX, INC. (US) | 1997-07-10 | — | — | WO | disclosed |