⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963881 | 0.92 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL11808518 | 0.90 | TSHR (0.41) | — | |
| SCHEMBL8688535 | 0.89 | LMNA (0.39) | — | |
| SCHEMBL8688500 | 0.89 | LMNA (0.39) | — | |
| SCHEMBL2255083 | 0.89 | LMNA (0.39) | — | |
| SCHEMBL5067430 | 0.81 | — | — | |
| SCHEMBL823000 | 0.81 | — | — | |
| SCHEMBL25260973 | 0.80 | — | — | |
| SCHEMBL20483089 | 0.78 | — | — | |
| SCHEMBL9284273 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117106264-B | Anti-aging auxiliary agent composition and preparation method thereof | 合肥梓纯科技有限公司 | 2024-11-19 | — | — | CN | claimed |
| CN-117106264-A | Anti-aging auxiliary agent composition and preparation method thereof | 合肥梓纯科技有限公司 | 2023-11-24 | — | — | CN | claimed |
| CN-117106264-B | Anti-aging auxiliary agent composition and preparation method thereof | 合肥梓纯科技有限公司 | 2024-11-19 | — | — | CN | disclosed |
| CN-117106264-A | Anti-aging auxiliary agent composition and preparation method thereof | 合肥梓纯科技有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-110461826-B | Synthesis method of irinotecan and intermediate compound thereof | 浙江奥翔药业股份有限公司 | 2023-08-25 | — | — | CN | disclosed |
| EP-2743269-B1 | PIM KINASE INHIBITOR, PREPARATION METHOD AND USE THEREOF IN DRUG PREPARATION | JIKAI BIOSCIENCES INC (CN) | 2018-09-26 | — | — | EP | disclosed |
| US-9073885-B2 | Vitamin D3 lactone derivatives | TEIJIN PHARMA LIMITED (JP) | 2015-07-07 | — | — | US | disclosed |
| US-8969584-B2 | PIM kinase inhibitors and preparation methods and use in medicinal manufacture thereof | Jikai Biosciences, Inc. (CN) | 2015-03-03 | — | — | US | disclosed |
| EP-1589009-B1 | VITAMIN D3 LACTONE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2014-10-08 | — | — | EP | disclosed |
| EP-2743269-A1 | PIM KINASE INHIBITOR, PREPARATION METHOD AND USE THEREOF IN DRUG PREPARATION | Jikai Biosciences Inc. (CN) | 2014-06-18 | — | — | EP | disclosed |
| US-20140162998-A1 | PIM KINASE INHIBITORS AND PREPARATION METHODS AND USE IN MEDICINAL MANUFACTURE THEREOF | Jikai Biosciences, Inc. (CN) | 2014-06-12 | — | — | US | disclosed |
| EP-2111223-A1 | AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | Acucela, Inc. (US) | 2009-10-28 | — | — | EP | disclosed |
| WO-2009058216-A1 | AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA, INC. (US) | 2009-05-07 | — | — | WO | disclosed |
| US-20060148768-A1 | Vitamin d3 lactone derivatives | TEIJIN LIMITED (JP) | 2006-07-06 | — | — | US | disclosed |
| EP-1589009-A1 | VITAMIN D3 LACTONE DERIVATIVE | Teijin Pharma Limited (JP) | 2005-10-26 | — | — | EP | disclosed |
| US-3935342-A | POLYMERIZATION WITH AN UNSATURATED SILYL MONOMER | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-27 | — | — | US | disclosed |