Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 9/20 | 0.74 |
| ▸ | VHL | P40337 | 4/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17938029 | 0.99 | P4HTM (0.72) | P4HTMVHLEGLN1 | |
| Hydrochloric Acid SCHEMBL17938030 | 0.85 | P4HTM (0.62) | P4HTMVHLEGLN1 | |
| SCHEMBL8197743 | 0.85 | P4HTM (1.00) | P4HTMVHLEGLN1 | |
| Hydrochloric Acid SCHEMBL3618381 | 0.84 | P4HTM (0.98) | P4HTMVHLEGLN1 | |
| SCHEMBL17938039 | 0.84 | P4HTM (0.69) | P4HTMVHLEGLN1 | |
| SCHEMBL3593725 | 0.78 | VHL (0.70) | P4HTMVHLEGLN1 | |
| SCHEMBL3836020 | 0.74 | P4HTM (0.67) | P4HTMVHLEGLN1 | |
| SCHEMBL8195371 | 0.73 | P4HTM (0.71) | P4HTMVHLEGLN1 | |
| Hydrochloric Acid SCHEMBL3842101 | 0.73 | P4HTM (0.66) | P4HTMVHLEGLN1 | |
| SCHEMBL3595365 | 0.71 | VHL (0.71) | P4HTMVHLEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097404-A1 | SUBSTITUTED DIPYRIDYL-DIHYDROPYRAZOLONES AND USE THEREOF | Bayer HealthCare AG (DE) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008067874-A1 | SUBSTITUTED DIPYRIDYL-DIHYDROPYRAZOLONES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-06-12 | — | — | WO | disclosed |