Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | GFER | P55789 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 8/20 | 0.57 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.50 |
| ▸ | CDK2 | P24941 | 9/20 | 0.50 |
| ▸ | CCNE2 | O96020 | 7/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.50 |
| ▸ | CDK9 | P50750 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CDK4 | P11802 | 3/20 | 0.49 |
| ▸ | CCND1 | P24385 | 3/20 | 0.49 |
| ▸ | CDK7 | P50613 | 3/20 | 0.49 |
| ▸ | CCNH | P51946 | 3/20 | 0.49 |
| ▸ | CDK1 | P06493 | 2/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3841006 | 0.92 | MAPT (0.55) | MAPTMEN1KMT2AGFERRAB9A | |
| SCHEMBL3837458 | 0.86 | CCNE1 (0.53) | MAPTMEN1KMT2AGFERRAB9A | |
| SCHEMBL3837186 | 0.83 | MEN1 (0.60) | MAPTMEN1KMT2AGFERRAB9A | |
| SCHEMBL3837095 | 0.83 | GAA (0.52) | MAPTMEN1KMT2AGFERRAB9A | |
| SCHEMBL3842346 | 0.83 | MEN1 (0.60) | MAPTMEN1KMT2AGFERRAB9A | |
| SCHEMBL3837734 | 0.81 | GAA (0.72) | MAPTMEN1KMT2AGFERRAB9A | |
| SCHEMBL3841291 | 0.80 | GAA (0.56) | MAPTMEN1KMT2AGFERRAB9A | |
| SCHEMBL3839607 | 0.79 | GAA (0.48) | MAPTMEN1KMT2AGFERRAB9A | |
| SCHEMBL3839898 | 0.79 | GAA (0.52) | MAPTMEN1KMT2AGFERRAB9A | |
| SCHEMBL3837701 | 0.76 | GAA (0.56) | MAPTMEN1KMT2AGFERRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786779-B1 | 4-ARYLAZO-3,5-DIAMINO-PYRAZOLE COMPOUNDS AND USE THEREOF | INST OF EX BOTANY OF THE ASCR (CZ) | 2009-10-28 | — | — | EP | claimed |
| US-20080312238-A1 | 4-Arylazo-3,5-Diamino-Pyrazole Compounds and Use Thereof | INSTITUTE OF EXPERIMENTAL BONTANY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC, V.V.I. (CZ) | 2008-12-18 | — | — | US | claimed |
| EP-1786779-A1 | 4-ARYLAZO-3,5-DIAMINO-PYRAZOLE COMPOUNDS AND USE THEREOF | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2007-05-23 | — | — | EP | claimed |
| WO-2006024858-A1 | 4-ARYLAZO-3,5-DIAMINO-PYRAZOLE COMPOUNDS AND USE THEREOF | INSTITUTE OF EXPERIMENTAL BOTANY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2006-03-09 | — | — | WO | claimed |
| US-8357673-B2 | 4-arylazo-3,5-diamino-pyrazole compounds and use thereof | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2013-01-22 | — | — | US | disclosed |
| EP-1786779-B1 | 4-ARYLAZO-3,5-DIAMINO-PYRAZOLE COMPOUNDS AND USE THEREOF | INST OF EX BOTANY OF THE ASCR (CZ) | 2009-10-28 | — | — | EP | disclosed |
| US-20080312238-A1 | 4-Arylazo-3,5-Diamino-Pyrazole Compounds and Use Thereof | INSTITUTE OF EXPERIMENTAL BONTANY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC, V.V.I. (CZ) | 2008-12-18 | — | — | US | disclosed |
| EP-1786779-A1 | 4-ARYLAZO-3,5-DIAMINO-PYRAZOLE COMPOUNDS AND USE THEREOF | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006024858-A1 | 4-ARYLAZO-3,5-DIAMINO-PYRAZOLE COMPOUNDS AND USE THEREOF | INSTITUTE OF EXPERIMENTAL BOTANY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312238-A1 | 4-Arylazo-3,5-Diamino-Pyrazole Compounds and Use Thereof | CDK9, CDK3, CDK19 | MAPT 207/4885MEN1 4080/4885KMT2A 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.