Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.62 |
| ▸ | IL2 | P60568 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7631773 | 0.89 | BACE1 (0.77) | BACE1IL2POLBGAAMAPT | |
| SCHEMBL124603 | 0.89 | BACE1 (0.77) | BACE1IL2POLBGAAMAPT | |
| SCHEMBL124604 | 0.89 | BACE1 (0.77) | BACE1IL2POLBGAAMAPT | |
| Phenol SCHEMBL22345138 | 0.86 | BACE1 (0.71) | BACE1IL2POLBGAAMAPT | |
| Allicin SCHEMBL5451006 | 0.85 | BACE1 (0.63) | BACE1IL2POLBGAAMAPT | |
| SCHEMBL22400844 | 0.81 | BACE1 (0.64) | BACE1IL2POLBGAAMAPT | |
| Oleuropein SCHEMBL23133256 | 0.78 | BACE1 (1.00) | BACE1IL2POLBGAAMAPT | |
| Oleuropein SCHEMBL23559534 | 0.78 | BACE1 (1.00) | BACE1IL2POLBGAAMAPT | |
| Oleuropein SCHEMBL22220681 | 0.78 | BACE1 (1.00) | BACE1IL2POLBGAAMAPT | |
| Oleuropein SCHEMBL23133255 | 0.78 | BACE1 (1.00) | BACE1IL2POLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040696-A2 | COMPOSITIONS AND USE THEREOF FOR THE TREATMENT, CO-TREATMENT OR PREVENTION OF INFLAMMATORY DISORDERS | DSMIP Assets B.V. (NL) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008006581-A2 | COMPOSITIONS AND USE THEREOF FOR THE TREATMENT, CO-TREATMENT OR PREVENTION OF IMFLAMMATORY DISORDERS | DSM IP ASSETS B.V. (NL) | 2008-01-17 | — | — | WO | disclosed |