Oleuropein

Oleuropein

SCHEMBL23133255

C/C=C1/C(CC(=O)OCCc2ccc(O)c(O)c2)C(C(=O)OC)=CO[C@H]1O[C@@H]1OC(CO)[C@@H](O)C(O)C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 1.00
IL2 P60568 1/20 0.74
POLB P06746 2/20 0.58
MAPT P10636 2/20 0.58
KDM4E B2RXH2 1/20 0.58
GAA P10253 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
PRKCA P17252 4/20 0.44
ALDH1A1 P00352 1/20 0.42
CYP3A4 P08684 1/20 0.42
ALOX15 P16050 1/20 0.42
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 1/20 0.42
STAT3 P40763 7/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
KDM1A O60341 1/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP19A1 P11511 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oleuropein SCHEMBL22220681 1.00 BACE1 (1.00) BACE1IL2POLBMAPTKDM4E
Oleuropein SCHEMBL14209775 1.00 BACE1 (1.00) BACE1IL2POLBMAPTKDM4E
Oleuropein SCHEMBL21481089 1.00 BACE1 (1.00) BACE1IL2POLBMAPTKDM4E
Oleuropein SCHEMBL22598615 1.00 BACE1 (1.00) BACE1IL2POLBMAPTKDM4E
Oleuropein SCHEMBL23559534 1.00 BACE1 (1.00) BACE1IL2POLBMAPTKDM4E
Oleuropein SCHEMBL18843179 1.00 BACE1 (1.00) BACE1IL2POLBMAPTKDM4E
Oleuropein SCHEMBL23133256 1.00 BACE1 (1.00) BACE1IL2POLBMAPTKDM4E
Oleuropein SCHEMBL24452037 1.00 BACE1 (1.00) BACE1IL2POLBMAPTKDM4E
Oleuropein SCHEMBL22220678 1.00 BACE1 (1.00) BACE1IL2POLBMAPTKDM4E
Oleuropein SCHEMBL17934321 1.00 BACE1 (1.00) BACE1IL2POLBMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210088504-A1 PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2021-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210088504-A1 PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF SENP8, SENP6, SENP7 BACE1 1145/4885IL2 3306/4885POLB 4121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.