Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1640707 | 0.88 | F10 (0.36) | P2RY12GRM1F10 | |
| SCHEMBL1638830 | 0.87 | P2RY12 (0.35) | P2RY12GRM1F10 | |
| SCHEMBL3836854 | 0.87 | EGFR (0.36) | GRM1 | |
| SCHEMBL3840108 | 0.85 | P2RY12 (0.40) | P2RY12GRM1F10 | |
| SCHEMBL3836616 | 0.81 | MEN1 (0.34) | GRM1F10 | |
| SCHEMBL3839792 | 0.81 | EGFR (0.34) | GRM1F10 | |
| SCHEMBL3834826 | 0.81 | F10 (0.34) | F10 | |
| SCHEMBL3835105 | 0.80 | ROCK2 (0.36) | F10 | |
| SCHEMBL3834640 | 0.79 | MIF (0.33) | GRM1 | |
| SCHEMBL12727560 | 0.78 | F10 (0.37) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094272-A2 | NITROGEN CONTAINING SUBSTITUTED HETEROCYCLES AS PLATELET ADP RECEPTOR INHIBITORS | Portola Pharmaceuticals, Inc. (US) | 2009-09-02 | — | — | EP | claimed |
| WO-2008036843-A2 | NITROGEN CONTAINING SUBSTITUTED HETEROCYCLES AS PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2008-03-27 | — | — | WO | claimed |
| EP-2094272-A2 | NITROGEN CONTAINING SUBSTITUTED HETEROCYCLES AS PLATELET ADP RECEPTOR INHIBITORS | Portola Pharmaceuticals, Inc. (US) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008036843-A2 | NITROGEN CONTAINING SUBSTITUTED HETEROCYCLES AS PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2008-03-27 | — | — | WO | disclosed |