Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.60 |
| ▸ | CA2 | P00918 | 9/20 | 0.60 |
| ▸ | CA12 | O43570 | 8/20 | 0.60 |
| ▸ | CA9 | Q16790 | 8/20 | 0.60 |
| ▸ | RORC | P51449 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2638624 | 0.92 | CA1 (0.61) | CA1CA2CA12CA9RORC | |
| SCHEMBL4603317 | 0.87 | CA1 (0.61) | CA1CA2CA12CA9RORC | |
| SCHEMBL3837658 | 0.86 | CA12 (0.53) | CA1CA2CA12CA9RORC | |
| SCHEMBL2639161 | 0.83 | CA2 (0.59) | CA1CA2CA12CA9RORC | |
| SCHEMBL2639656 | 0.82 | CA1 (0.58) | CA1CA2CA12CA9RORC | |
| SCHEMBL2640024 | 0.81 | CA1 (0.59) | CA1CA2CA12CA9RORC | |
| SCHEMBL2639462 | 0.81 | CA1 (0.56) | CA1CA2CA12CA9RORC | |
| SCHEMBL14625926 | 0.80 | P2RX4 (0.59) | CA1CA2CA12CA9POLB | |
| SCHEMBL2638691 | 0.75 | CA1 (0.61) | CA1CA2CA12CA9RORC | |
| SCHEMBL13581454 | 0.74 | CA1 (0.70) | CA1CA2CA12CA9RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742908-B1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-11-11 | — | — | EP | disclosed |