Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3838373 | 0.83 | NR1H4 (0.50) | NR1H4ELANE | |
| SCHEMBL3835251 | 0.83 | NR1H4 (0.44) | NR1H4ELANE | |
| SCHEMBL4618555 | 0.82 | NR1H4 (0.46) | NR1H4ELANE | |
| SCHEMBL5721660 | 0.82 | NR1H4 (0.45) | NR1H4ELANE | |
| SCHEMBL4598886 | 0.82 | NR1H4 (0.43) | NR1H4ELANE | |
| SCHEMBL14677996 | 0.82 | NR1H4 (0.48) | NR1H4ELANE | |
| SCHEMBL4665640 | 0.81 | NR1H4 (0.44) | NR1H4ELANE | |
| SCHEMBL4598052 | 0.81 | NR1H4 (0.51) | NR1H4ELANE | |
| SCHEMBL6026583 | 0.81 | NR1H4 (0.47) | NR1H4ELANE | |
| SCHEMBL6989461 | 0.81 | NR1H4 (0.51) | NR1H4ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430040-A1 | BENZOTHIAZEPINE DERIVATIVES | Astrazeneca AB (SE) | 2004-06-23 | — | — | EP | claimed |
| WO-2003020710-A1 | BENZOTHIAZEPINE DERIVATIVES | ASTRAZENECA AB (SE) | 2003-03-13 | — | — | WO | claimed |
| EP-2013165-A1 | DIPHENYLAZETIDINONE DERIVATES POSSESSING CHOLESTEROL ABSOR TION INHIBITOR ACTIVIT. | Astra Zeneca AB (SE) | 2009-01-14 | — | — | EP | disclosed |
| EP-1885694-A2 | 4-BIARYLYL-1-PHENYLAZETIDIN-2-ONES | Microbia, Inc. (US) | 2008-02-13 | — | — | EP | disclosed |
| WO-2007126358-A1 | DIPHENYLAZETIDINONE DERIVATES POSSESSING CHOLESTEROL ABSOR TION INHIBITOR ACTIVIT. | ASTRAZENECA AB (SE) | 2007-11-08 | — | — | WO | disclosed |
| WO-2006124713-A2 | 4-BIARYLYL-1-PHENYLAZETIDIN-2-ONES | MICROBIA, INC. (US) | 2006-11-23 | — | — | WO | disclosed |
| EP-1699759-A1 | DIPHENYLAZETIDINONE DERIVATES POSSESSING CHOLESTEROL ABSORPTION INHIBITORY ACTIVITY | AstraZeneca AB (SE) | 2006-09-13 | — | — | EP | disclosed |
| EP-1699758-A1 | DIPHENYLAZETIDINONE DERIVATES PROCESSING CHOLESTEROL ABSORPTION INHIBITORY ACTIVITY | AstraZeneca AB (SE) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005061451-A1 | DIPHENYLAZETIDINONE DERIVATES PROCESSING CHOLESTEROL ABSORPTION INHIBITORY ACTIVITY | ASTRAZENECA AB (SE) | 2005-07-07 | — | — | WO | disclosed |
| WO-2005061452-A1 | DIPHENYLAZETIDINONE DERIVATES POSSESSING CHOLESTEROL ABSORPTION INHIBITORY ACTIVITY | ASTRAZENECA AB (SE) | 2005-07-07 | — | — | WO | disclosed |