Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CAPNS1 | P04632 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 3/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4598052 | 0.95 | NR1H4 (0.51) | NR1H4ELANECAPNS1CAPN1CTSD | |
| SCHEMBL3834784 | 0.94 | NR1H4 (0.50) | NR1H4ELANECAPNS1CAPN1CTSD | |
| SCHEMBL4619436 | 0.94 | NR1H4 (0.50) | NR1H4ELANECAPNS1CAPN1CTSD | |
| SCHEMBL5706907 | 0.92 | NR1H4 (0.49) | NR1H4ELANECAPNS1CAPN1CTSD | |
| SCHEMBL3831703 | 0.92 | NR1H4 (0.51) | NR1H4ELANECAPNS1CAPN1CTSD | |
| SCHEMBL3838373 | 0.92 | NR1H4 (0.50) | NR1H4ELANECAPNS1CAPN1CTSD | |
| SCHEMBL14677996 | 0.92 | NR1H4 (0.48) | NR1H4ELANECAPNS1CAPN1CTSD | |
| SCHEMBL4598195 | 0.92 | NR1H4 (0.50) | NR1H4ELANECAPNS1CAPN1CTSD | |
| SCHEMBL14677825 | 0.92 | NR1H4 (0.62) | NR1H4ELANECAPNS1CAPN1 | |
| SCHEMBL5709066 | 0.91 | NR1H4 (0.56) | NR1H4ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345918-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050051-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2002-06-27 | — | — | WO | disclosed |