Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 4/20 | 0.48 |
| ▸ | MC1R | Q01726 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4468315 | 0.83 | KMT2A (0.71) | KMT2AMEN1OPRM1OPRD1GAA | |
| SCHEMBL4477437 | 0.83 | KMT2A (0.71) | KMT2AMEN1OPRM1OPRD1GAA | |
| SCHEMBL4466517 | 0.83 | KMT2A (0.71) | KMT2AMEN1OPRM1OPRD1GAA | |
| SCHEMBL4486265 | 0.83 | KMT2A (0.71) | KMT2AMEN1OPRM1OPRD1GAA | |
| SCHEMBL4474689 | 0.83 | KMT2A (0.71) | KMT2AMEN1OPRM1OPRD1GAA | |
| SCHEMBL4818799 | 0.81 | CYP2D6 (0.67) | OPRM1OPRD1GAAKDM4EALDH1A1 | |
| SCHEMBL18704990 | 0.81 | KMT2A (0.73) | KMT2AMEN1OPRM1OPRD1GAA | |
| Acetic Acid SCHEMBL9325415 | 0.81 | GAA (0.75) | KMT2AMEN1OPRM1OPRD1GAA | |
| SCHEMBL4872366 | 0.79 | ALDH1A1 (0.57) | KMT2AMEN1GAAKDM4EALDH1A1 | |
| SCHEMBL10746494 | 0.79 | GAA (0.82) | KMT2AMEN1OPRM1OPRD1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1553092-B1 | ARALKYL FORMYL-ALKYL PIPERAZINE DERIVATIVES AND THEIR USES AS CEREBRAL NERVE PROTECTIVE AGENT | SHANGHAI INST PHARM INDUSTRY (CN) | 2009-11-04 | — | — | EP | claimed |